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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for THBD (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7056 Official gene symbol THBD Full name thrombomodulin Aliases ,AHUS6,CD141,THRM,TM, Gene summary The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq] Location Chromosome: 20   Locus: 20p11.2 Gene position 23030301 - 23026270  Map Viewer Gene orientation minus Gene size 4032 bp Gene sequence >THBD:complement(22966270..22970301):Length=4032 GGCTGCCTCGCAGGGGCTGCGCGCAGCGGCAAGAAGTGTCTGGGCTGGGACGGACAGGAG AGGCTGTCGCCATCGGCGTCCTGTGCCCCTCTGCTCCGGCACGGCCCTGTCGCAGTGCCC GCGCTTTCCCCGGCGCCTGCACGCGGCGCGCCTGGGTAACATGCTTGGGGTCCTGGTCCT TGGCGCGCTGGCCCTGGCCGGCCTGGGGTTCCCCGCACCCGCAGAGCCGCAGCCGGGTGG CAGCCAGTGCGTCGAGCACGACTGCTTCGCGCTCTACCCGGGCCCCGCGACCTTCCTCAA TGCCAGTCAGATCTGCGACGGACTGCGGGGCCACCTAATGACAGTGCGCTCCTCGGTGGC TGCCGATGTCATTTCCTTGCTACTGAACGGCGACGGCGGCGTTGGCCGCCGGCGCCTCTG GATCGGCCTGCAGCTGCCACCCGGCTGCGGCGACCCCAAGCGCCTCGGGCCCCTGCGCGG CTTCCAGTGGGTTACGGGAGACAACAACACCAGCTATAGCAGGTGGGCACGGCTCGACCT CAATGGGGCTCCCCTCTGCGGCCCGTTGTGCGTCGCTGTCTCCGCTGCTGAGGCCACTGT GCCCAGCGAGCCGATCTGGGAGGAGCAGCAGTGCGAAGTGAAGGCCGATGGCTTCCTCTG CGAGTTCCACTTCCCAGCCACCTGCAGGCCACTGGCTGTGGAGCCCGGCGCCGCGGCTGC CGCCGTCTCGATCACCTACGGCACCCCGTTCGCGGCCCGCGGAGCGGACTTCCAGGCGCT GCCGGTGGGCAGCTCCGCCGCGGTGGCTCCCCTCGGCTTACAGCTAATGTGCACCGCGCC GCCCGGAGCGGTCCAGGGGCACTGGGCCAGGGAGGCGCCGGGCGCTTGGGACTGCAGCGT GGAGAACGGCGGCTGCGAGCACGCGTGCAATGCGATCCCTGGGGCTCCCCGCTGCCAGTG CCCAGCCGGCGCCGCCCTGCAGGCAGACGGGCGCTCCTGCACCGCATCCGCGACGCAGTC CTGCAACGACCTCTGCGAGCACTTCTGCGTTCCCAACCCCGACCAGCCGGGCTCCTACTC GTGCATGTGCGAGACCGGCTACCGGCTGGCGGCCGACCAACACCGGTGCGAGGACGTGGA TGACTGCATACTGGAGCCCAGTCCGTGTCCGCAGCGCTGTGTCAACACACAGGGTGGCTT CGAGTGCCACTGCTACCCTAACTACGACCTGGTGGACGGCGAGTGTGTGGAGCCCGTGGA CCCGTGCTTCAGAGCCAACTGCGAGTACCAGTGCCAGCCCCTGAACCAAACTAGCTACCT CTGCGTCTGCGCCGAGGGCTTCGCGCCCATTCCCCACGAGCCGCACAGGTGCCAGATGTT TTGCAACCAGACTGCCTGTCCAGCCGACTGCGACCCCAACACCCAGGCTAGCTGTGAGTG CCCTGAAGGCTACATCCTGGACGACGGTTTCATCTGCACGGACATCGACGAGTGCGAAAA CGGCGGCTTCTGCTCCGGGGTGTGCCACAACCTCCCCGGTACCTTCGAGTGCATCTGCGG GCCCGACTCGGCCCTTGCCCGCCACATTGGCACCGACTGTGACTCCGGCAAGGTGGACGG TGGCGACAGCGGCTCTGGCGAGCCCCCGCCCAGCCCGACGCCCGGCTCCACCTTGACTCC TCCGGCCGTGGGGCTCGTGCATTCGGGCTTGCTCATAGGCATCTCCATCGCGAGCCTGTG CCTGGTGGTGGCGCTTTTGGCGCTCCTCTGCCACCTGCGCAAGAAGCAGGGCGCCGCCAG GGCCAAGATGGAGTACAAGTGCGCGGCCCCTTCCAAGGAGGTAGTGCTGCAGCACGTGCG GACCGAGCGGACGCCGCAGAGACTCTGAGCGGCCTCCGTCCAGGAGCCTGGCTCCGTCCA GGAGCCTGTGCCTCCTCACCCCCAGCTTTGCTACCAAAGCACCTTAGCTGGCATTACAGC TGGAGAAGACCCTCCCCGCACCCCCCAAGCTGTTTTCTTCTATTCCATGGCTAACTGGCG AGGGGGTGATTAGAGGGAGGAGAATGAGCCTCGGCCTCTTCCGTGACGTCACTGGACCAC TGGGCAATGATGGCAATTTTGTAACGAAGACACAGACTGCGATTTGTCCCAGGTCCTCAC TACCGGGCGCAGGAGGGTGAGCGTTATTGGTCGGCAGCCTTCTGGGCAGACCTTGACCTC GTGGGCTAGGGATGACTAAAATATTTATTTTTTTTAAGTATTTAGGTTTTTGTTTGTTTC CTTTGTTCTTACCTGTATGTCTCCAGTATCCACTTTGCACAGCTCTCCGGTCTCTCTCTC TCTACAAACTCCCACTTGTCATGTGACAGGTAAACTATCTTGGTGAATTTTTTTTTCCTA GCCCTCTCACATTTATGAAGCAAGCCCCACTTATTCCCCATTCTTCCTAGTTTTCTCCTC CCAGGAACTGGGCCAACTCACCTGAGTCACCCTACCTGTGCCTGACCCTACTTCTTTTGC TCTTAGCTGTCTGCTCAGACAGAACCCCTACATGAAACAGAAACAAAAACACTAAAAATA AAAATGGCCATTTGCTTTTTCACCAGATTTGCTAATTTATCCTGAAATTTCAGATTCCCA GAGCAAAATAATTTTAAACAAAGGTTGAGATGTAAAAGGTATTAAATTGATGTTGCTGGA CTGTCATAGAAATTACACCCAAAGAGGTATTTATCTTTACTTTTAAACAGTGAGCCTGAA TTTTGTTGCTGTTTTGATTTGTACTGAAAAATGGTAATTGTTGCTAATCTTCTTATGCAA TTTCCTTTTTTGTTATTATTACTTATTTTTGACAGTGTTGAAAATGTTCAGAAGGTTGCT CTAGATTGAGAGAAGAGACAAACACCTCCCAGGAGACAGTTCAAGAAAGCTTCAAACTGC ATGATTCATGCCAATTAGCAATTGACTGTCACTGTTCCTTGTCACTGGTAGACCAAAATA AAACCAGCTCTACTGGTCTTGTGGAATTGGGAGCTTGGGAATGGATCCTGGAGGATGCCC AATTAGGGCCTAGCCTTAATCAGGTCCTCAGAGAATTTCTACCATTTCAGAGAGGCCTTT TGGAATGTGGCCCCTGAACAAGAATTGGAAGCTGCCCTGCCCATGGGAGCTGGTTAGAAA TGCAGAATCCTAGGCTCCACCCCATCCAGTTCATGAGAATCTATATTTAACAAGATCTGC AGGGGGTGTGTCTGCTCAGTAATTTGAGGACAACCATTCCAGACTGCTTCCAATTTTCTG GAATACATGAAATATAGATCAGTTATAAGTAGCAGGCCAAGTCAGGCCCTTATTTTCAAG AAACTGAGGAATTTTCTTTGTGTAGCTTTGCTCTTTGGTAGAAAAGGCTAGGTACACAGC TCTAGACACTGCCACACAGGGTCTGCAAGGTCTTTGGTTCAGCTAAGCTAGGAATGAAAT CCTGCTTCAGTGTATGGAAATAAATGTATCATAGAAATGTAACTTTTGTAAGACAAAGGT TTTCCTCTTCTATTTTGTAAACTCAAAATATTTGTACATAGTTATTTATTTATTGGAGAT AATCTAGAACACAGGCAAAATCCTTGCTTATGACATCACTTGTACAAAATAAACAAATAA CAATGTGCTCTCGGGTTGTGTGTCTGTTCACTTTTCCTCCCTCAGTGCCCTCATTTTATG TCATTAAATGGGGCTCACAAACCATGCAAATGCTATGAGATGCATGGAGGGCTGCCCTGT ACCCCAGCACTTGTGTTGTCTGGTGGTGGCACCATCTCTGATTTTCAAAGCTTTTTCCAG AGGCTATTATTTTCACTGTAGAATGATTTCATGCTATCTCTGTGTGCACAAATATTTATT TTCTTTCTGTAACCATAACAACTTCATATATGAGGACTTGTGTCTCTGTGCTTTTAAATG CATAAATGCATTATAGGATCATTTGTTGGAATGAATTAAATAAACCCTTCCTGGGGCATC TGGCGAATCCCA OMIM ID 188040