| Entrez gene ID | | 7171 |
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| Official gene symbol | | TPM4 |
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| Full name | | tropomyosin 4 |
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| Aliases | | ,-, |
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| Gene summary | | This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 19 Locus: 19p13.1 |
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| Gene position | | 16178317 - 16213813 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 35497 bp |
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| Gene sequence |
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