Entrez gene ID | | 7184 |
Official gene symbol | | HSP90B1 |
Full name | | heat shock protein 90kDa beta (Grp94), member 1 |
Aliases | | ,ECGP,GP96,GRP94,TRA1, |
Gene summary | | HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM] |
Location | | Chromosome: 12 Locus: 12q24.2-q24.3 |
Gene position | | 104324189 - 104341703 Map Viewer |
Gene orientation | | plus |
Gene size | | 17515 bp |
Gene sequence |
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OMIM ID | | 191175 |
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