Entrez gene ID | | 7188 |
Official gene symbol | | TRAF5 |
Full name | | TNF receptor-associated factor 5 |
Aliases | | ,MGC:39780,RNF84, |
Gene summary | | The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q32 |
Gene position | | 211499957 - 211548288 Map Viewer |
Gene orientation | | plus |
Gene size | | 48332 bp |
Gene sequence |
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OMIM ID | | 602356 |
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