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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRHR (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7201
Official gene symbolTRHR
Full namethyrotropin-releasing hormone receptor
Aliases,MGC141920,
Gene summaryThyrotropin-releasing hormone (TRH; MIM 275120), a small neuropeptide, is widely distributed throughout the central and peripheral nervous system as well as in extraneural tissues. The peptide is synthesized in the hypothalamus and transported by the portal vascular system to the anterior pituitary where it acts on thyrotropic and lactotropic cells to promote secretion of TSH and prolactin, respectively. Thyrotropin-releasing hormone receptor is a G protein-coupled receptor that activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon the binding of TRH. The TRHR gene is expressed in the thyrotrope cells of the anterior pituitary.[supplied by OMIM]
LocationChromosome: 8   Locus: 8q23
Gene position110099676 - 110131813  Map Viewer
Gene orientationplus
Gene size32138 bp
Gene sequence
OMIM ID188545