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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for C4BPB (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 725 Official gene symbol C4BPB Full name complement component 4 binding protein, beta Aliases ,C4BP, Gene summary This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq] Location Chromosome: 1   Locus: 1q32 Gene position 207262212 - 207273338  Map Viewer Gene orientation plus Gene size 11127 bp Gene sequence >C4BPB:779991..791117:Length=11127 GACTTTGGAGCTCTCAGCTTTGGAGTCAGTTAAGACCAGTTCCTTGCTGGGAAGCCCTAA CTCTGGAGGGACAGAGACAGGTAAGGTTAGTTTACTTCCTTGAGCTTTCGTCTTCAGTGC TGCTTACAGCCTTAGGATATCTGGTATTCAGGAAAGGAGGATGAGGTAGCATTCAAAATT GTGTTCTACCTGGGCAAGAACCAGGGATTGACAGCCCGTTCTCTTTCCCCAGTGCTGGCC AGAGTTACAGAAGTTGGACTGTAAACATTGGCAACTATTGACAGAAGTCAAGGTCATGGC AAGACCATTTGGCCCATGTTTGTTGGGGAAGGATAAGCCTGCGTTTCAAAAAGACTGGTC AACTGGATTTGCATTCCCAGAAACCAGGAAATTTCTGAAACTGAGTTTTAAACCTGGCAA CTCTTTTACCATCCCTTTGTATTTTTGCAGTTCCTCCCTATACCAGCTTCCTTACAGCTG TTCTGATTTCCTGTCGTAAGATTTTTTCTTTTCATTTTCTCCAGGGAGGGTAAATCAATA TAACCTCTTCTCTAGAGAGGAGGTGGTTAGGTTGGTCTTAAGCAGTGTTAGAAGATCTAT TTTTTTTCAAACCAGGTGTCTGAGCTGGGTGAATTCCAGCCTGGGGAGAGGACTTTGATC ACCAGATGTTTTTTTGGTGTGCGTGCTGTCTTATGGTTGCGTGGCGAGTTTCTGCTTCAG ATGGTACGTATGCTTTCCTTCAACTCAGCTTACAGGCATTTGGTGTCCTTTTGCGGTGTT TTGAGGAACTCTGTCTAGGGCTTTAAGGAAGTTTACATTTATAATATCTTTATTCTTCTA TTGAAAAATCTCAAATTGGCCTAATGCTCTGCACTCAATAGGAGCTTAGTGTACATTTAA TGATAACCCTGATCTCTGAAGTGGGTGGTTACTGTTTTTTTACTTTCCCTTTCTGTTCTG GGAGCAAAAAGAGTACCAATTTCAAAATCCTGGGAGGTCTTACTTGTTATAAACTCCAGG ATCGCTATTTGTGTAGGGGACTATTTGTTTAGAAGTGGACAACTTGTGGTTGAATTTGAG TAAAATTCCTGTTATACTTTTGAAAATAAAACTTCGGAATTCCGGCCGGGCGCAGCGGCT CAAGCCTGTAATCCCGGCACTTTGAGAGGCCGAGGTGGGCGGATCACGAGGTCAAGAGAT CGAGACCATCCTGGCTAAGACAGTGAAACCCCGTCTCTGCTGAAAATACAAAAAATTAGC TGGGCGTGGTGGCGGGTGCCTGTAGTCCCGGCTACTTGGGAGTAGAATACAGAGTACTTG GGAAGAGCACAGGAATCAGGATCAATAATCCAGCAAAAAGACATGAGAATGGGGAAATCT AATAAGGGTTCTCTGACAGCACATGATATGCCAAGTGAATCTGTTTTCTTTTTTCTTCCA GCAGAGCACTGTCCAGAGCTTCCTCCAGTGGACAATAGCATATTTGTCGCAAAGGAGGTG GAAGGACAGATTCTGGGGACTTACGTTTGTATCAAGGGCTACCACCTGGTAGGAAAGAAG ACCCTTTTTTGCAATGCCTCTAAGGAGTGGGATAACACCACTACTGAGTGCCGCTGTAAG TTAGATCTTTCTGTATCTTTGCCCATATTGATATCCTGTTTTACTCCTTCACATCCTACT TCCTATAGGCTGTGGTAAAACTTTATAAGAAAACAAAAATTCTCAATTTCTAGGAGACCT CTTTTAAAGCACTCCAGTGGAGGAGCTTCTCTTGGAAGCTCTATGATCAGATCTTGATCA GTATTAATTCAGTTGAATTAACAGAATCAATTCCCTCTATGGGAAAGAAATAATTTCTTC CAGATATTAGAACTAATTTTTTTTTGCTATAATTTGTTTAACCTTATATTGCTTTAAAAA TGTTTATGTTATGGAAAATTTAAAATGTATACAAACGACAGAAGAGTCAAATTCACTCAT ATAGACTCATCACATAATTTCATCAATTATCCACACATGATAATCTTGTTTCATGTATAT CCTCTTTATTATTTTGAAGTAAGTGCATTGTATCATTTTATTTCACCTATCATATAACTT TTGAACTGGGAATAGTTTGTATTCTCAGTTTACCAATGTGATAATTGAGATCCAGCTGAC TTGCTCAAGGTCACAAAACTCATTTCTGGTATCCTCTGTGGAGATGGGGAATAATTAATC CATATCCTATTTATTACTATTATTTTTTAAAGAATAGTTGCATTAGTTCTCTTGTATACC TAGAGTAGAGCACACCGATATTATTATCCTTCATTCATATAACCAAACTCATATATCCCT GTGCATTCTCTCCTGTTTTTTTCCATGCCATGGGAAAAAGCACAACAAAATAAAAAATGC TAAGTAAGTGTATATTTGGCTGGTTGAAAGGGAAGGAAATACTTGCTTCAAACATAGTCT CACTATTTTGAGCCATGCTTAATATAACAGTACAATAAACATACGATTGGTAACTTTCAG TTACGTGATTAATTACTTTCAGTTGCCAATTCATGTTGTTCTTGTGCATGACAAAGCTCT TTTGGGCTGTACTTAGGTCAATCTCCTCTTTTTTTCATTCTGCATTGATATGGTAGTACC ATGTACTTCACTCAATTAAAAATGTGCAGTATTAACTCTAATTTGCTGTTTTCTCACTGA AGACTGAGGAGGTCTGGCCTTTGCTGTGTTGGGCTTCAGCTTTGCCCTTTCAGCTTATTG CTTATTTTCTTCTTCAGTGGGCCACTGTCCTGATCCTGTGCTGGTGAATGGAGAGTTCAG TTCTTCAGGGCCTGTGAATGTAAGTGACAAAATCACGTTTATGTGCAATGACCACTACAT CCTCAAGGGCAGCAATCGGAGCCAGTGTCTAGAGGACCACACCTGGGCACCTCCCTTTCC CATCTGCAAAAGTAGTAAGTACAAGAGAAACCATCAAGGATCCCCAAAATACTGATTAGT AGTCTAAACTTAGACATTTGCCACATCCCTGGGATGCTTTTCTCTTTTTTTGTATCAGAG ACAGGCTTAAGATCTAGCAGACAGCCATGAAACAAGTGGAGCTCACAGAACCAAATCTCA CCTCAAGAGAATACATTCCATTGCAATGAACAGCATCCAAAGCACACATTTTTCCTTCTC AGATAGGGGTCCTGTCCTACTAGGTGTAATGTAGGGTAGTTTGGAGCATCGACTATTTTA TTTCTTAATTTCAAGACAGTGACTTTGTTTGAAAAGTAAACACAAAACGGGAAAAAGATC ATAACTCATCTATTGCAAAATTATCTACAAGAGGCTAAAGACCCTCTTTCTATCACTACA ATTCATATCTCTCAGAGTTAGTAAATTGGGTGTGTTTATTTCATGACTTTTTCTTATGTT TATACAGACATTTAAAACAAACACACACAAATAAAATATTTAAATTAAATAAGCATTAAA TGCCATTTTGTGTGTATGTATATATATAAATATACCTATAGAAAAGGGACTTGCTATACA TATTTTTAAATTGCTTTTTTTCATGTAACTATATACATGGCCACTTTCCTACACCAGTCC ATGTAGCTCTATTGCCCGCTATTTAATAACTGCATATGTGTATGTCATAATTTATTATAT GGCTCCCATATTATTTTAATATTTTTTATATTTGGAACAATGCTGAAATGAATATTTTAT ACACACACATATTCTTATGTCTACGTTGTTATTTCTTTCTTTCTTTTTTTTTTTTTTTTG AGATGGAGTCTTACTCTATTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGC AACCTCTGCTGCCCAGGTTCTAGCGATTCTGCTGCCTCAGCCTCCCGAGTAGCTGGGTTA CAGGTGCCTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACC ATCTTGGCCAGACTGGTCTTGAACTCCTGATCTCGTGATCCACCCACCTCGGCCTCCTAA AGTGCTGGGATTACAGGCGTGAGCCACCGCACCAGGCTACTACATTGCTATTTCTATAGG ATAGATTCCTAAAATGATTGCTGGATCACAGGATGCTATTATTTGCAGAATATACTTCAA ATATCCAAGAAAGTCTACTAAAATATTTAATATATACTTGGACACAAAATAAATATTGAA AAAAATCAATGTTTTCATTTTCTATTAATAATTGTTAGTTGAATTTGAAATGTAAAAATA ATTCGATTCACAAGATCTATATGAAAATTTACTGAAAGATATAAAATAAGACTTGAATGA AAGAAAAGACATGCATGATCCTGGATGGGCAGACTTACTATTACAGTGCAATGCCTCCCA GGATTTTAAATTCAAAAATATGAAAAAAACATTAATTAAAGAATCTCATCCAGTAGGATA CACATCTAACATTGTAAATATTTTTGGGAAAATGATGAATGATGTATACATTTGACTGGA TCAAAGGGAAAGGAATACTTGCCGTATTAGATAGTAAAAAATACTACAAAGTTACTATGA GCACAATATGGCAAACTGTAGGTACTACAAATTATATATCATTAAAATAGCAAAGTATAG GTACATATAAGTAGAACAGATTAAGTCAGGAGGAAAAGTCTATTCAATAGTGATGGAATA ATTATCTATTTGGAAGAAGACAAAGTTAGGGCTCTAGCTCACACCATATTCATAATACAT TCCAAATGGATTTTAAATATATAACTATAGAAAGCAAAATTATTAAATCATTAAAAGAAA ACATGAGATAATATATTTATTACATTGGGATGGGGAAAGCCTTCCTAAGCAGTTTCATAA AACTCAGGAAGTCATAAAGGAAGAAAATGGGCAGATTTAATTAAATTTTTAAAAGAAAAA CTTCTACATACTAAAAGACATCATATTGAATAAAGTATTTGCAACATATTTGATGGTTAA AGAGTTAATGTTTTTAATAAACAAAGATCCCCTAGAGATCAGTAAGGAAAAAAACAACCC AATAGAAAATAAGCAGTTGGGTAAGGACAGGCAATTCCAAAATAATGGCCCTAAACAGCA CTTCTATCTCCTGATTATATGAAAGGATATTGAACATTACAAATGATTATAGAACTGGAA ATTAAAATTAGATATACATCTTTTACTGATCAGATTAGCAAAAAATGAAAAGATGGATTT AATTTAATACTATTCATGACCTGAGGAAATAGCCATTTACGTCAGTGAGAGTGTAAAGTG CTATCACTATTTGGATGTATTTTGGCAGTAGCTACTAAAATAATAAAAGCCAGGCGTGGC AGTGCATACCTGCAGTCCCAGCTACTTGGGAAGCTAAGGCAGGAGGATAGCTTGAGTCCA GAAATTTGAGGCCAGCCTAGACAACACAGTGAGGCCTGTCTCTAAAAAAAAAAAAATGAA AAAGAAATAATAAAGACAGGCAGTTTAAGAGCACAAACTATATATGCTCTTACATGAGGG AATTTGGGGTTATTTAAAACTTGCATACATACTATTATATATACAGTTAAATTACATGCA TATAATAGCATTTTATGTCATTAGCTTGACACAAGTTTAAAGTATTTCCTTATTTCTTCC AAACATTTTCTGGTTTACTCTCTTTTAATTCAGTAGTTTCTATCCTAGCTCTTAACCACA GGATCCCTGTCTTTTTATGTCACTTCATTATCTAAATCTAGGATGAGCTCCCTAGGTTTC TGAATAAACCAGATTCTTTCTGTTTATTCTGTTTACCACATCATCTCCTTCCGTTCAAAA TTGTACTCATAAAAGTTACCAGAACTCTGGTGGACTGGAATCCCCCAAACAACTCCTGGA AATTCTTCTTGCTTTCCTCTATTCAGCCTTTGAGCTCAGTCTCTGAGCTTTAAAAAATTA CAGTGTATTAACTGCATAAGTAATATTAATACACCTTTGTTGTAGAAAAATATAGAAAAT AAAAGACGAAACCAATTACATACAAGCCATCTAAGGATAAGGGCATTAAGTATTTTGGCA TATAACTTTCCATACTTTTTTCCTGTGCTTATGTATGTGTAACCATGATTTACAAAAATA ATATTATACATGCTCTTTCATCATCTGCTGTTTTTACTCAACCATTTGTTTAGAAGATTT TTATGTTTCAGTAAATATACACCCACATAATCATTGTTAGCCACTATTTTTGATCGACAT GTTTAGTGTCCTGTGGTCTCAGAGCTGACTGGGACCTTAGAGATGATATTATTTAACCTG CTTATCTGATAATATTAGGAAGGAAGCCAAGAGGAGCAAAATGGCTTTAGTGCTACATAG CTAGTGGAAGAGCCAGTATCAAGACTCACAACTCCTAACACGTCATCCTGCTTTCTTTCC ACAGTTCCACAGACTCGTCCTCTTCCCTTCCAGCCATGTTCTCCCCTATTTCTTTTTCTT TTGAGACAGAGTCTTGCTCTGTTTCCCAGGCTGGAGTGCAGTGGCAGAATCTTGGCTCAC TGCAACCTCCACCTCCCAGGTTCAAGCAGTTCTCATGCCTCAGCCTCCCAAGTAGCTGGG ATTACAGGTGCGCACCCACGCTGGGCTAATTTTTGTATTTTTAGTAGAGACTGGGTTTCA CCATGTTGGCCAGGCTGGTCTCAAATTCCTGACCTCAGGTGATCCACCCCCTTCAGCCTC CCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCTCCCACCTTCTCCCCTTTTTCTGATA CTCTCTTTGATATAGTTTGGATGTGTGTTCCTGCTCAAATCTCATATTGAATTGTAATCT CCAGTGTTGGAGGTGGTGCTTGGTGGGAGGTGACTGGATCATGCGGGTGGATTTCTCATG AATGGTCTAGCACCATCTCCCTAGGTACTGTCCTCATGACAGCGAGTGAGTTCTCATGAG ATCTGGTTGTTTAAAAGTGTGTAACGCCTCCTCCCTCTCTCGTTCCTGCACCTGTTATGT GAGATGCCTCCCTCCCCCTTTGCCTTCTGCCATGATTGTAAGTTTTCCGAGGCCTCCCCA GAAGCCGAGCAGATGCCAGCACCATGTTTCCTGTACAGCCTGCAGAACTGTGAGCCAATT AAACCTCTTTTCTTTATAAATTACCCAGTCTCAGGTATTTCTGTATCACAATGTGAGATG GACTAATACACTCATGTTTCACAACTCTTATCCACAGGGGATGTCAGCTTCCACTTGAGC TCACACGCTTCATCTCCTCTCTCAGGGAGTTATTTCTTCAGCCTTCACCTATGGCCCAAT TTTTCTTTTCTTGTACATTAACAATTAGCTTCTCTACAACTTAAAATTTCTTTCCTTGAG CTCCTGCTGTCAGATAATACTCCCAAATCCCTACTAACTCAGAAGATGGGCTGGGGGAAA GCTCTTTCCCATGGACAAATATGATTTAGAAGAGAAGGAAATGAATGAAGAACAGGTTTC CAGATCCCGCAGGTGTTGCTGTGAGGATGTCAGGTGCTGGCGCAGGTGTTGCTCTGAGGC TGTCAGGTGCTGGCATAAACAGCTGCAATTAGGGGTGCTGTTCATTGAGCGTGCCTGGCC CTCATAACTATGACTTCTATACTCGTTTCTCTCAGGGGACTGTGACCCTCCTGGGAATCC AGTTCATGGCTATTTTGAAGGAAATAACTTCACCTTAGGATCCACCATTAGTTATTACTG TGAAGACAGGTAAGTGAACACAGCCTGTCAAATGCCAGATCTTGCCCCTTGGCAGCATTG TTTTGGGGAATAACCCAGTCTGTGTCCACCTGGTCATCTGATTTCCTACTGCTGCAGGAT TCTAAGCTCATTCTGATTTTGAGAGCTGCTTTGGCCCTCTGCTAGCTCTCCTCAATCCCT AGAAGACAGACTGATCCTACTAAAGTATCCTACTTACCCCAATGCAAGTATCTCTTTTTC CTCTCCGCCAAGACAAGATAAATTATTTAAAATGAATGGATTTGGCTGGGCGTGATGGCT CACACCTGTAATCCCAGCACTTTGGGATGCTAAGGCAGGCGGTTTGCTTGAGGCCAGGAG ATCAAGACCAGCCTGGCCAACATGGCAAAACCCTTGTCTCTACTAAAAATACAAAAATTA GCTGGGCGTGGTGGCACACTCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCATGAGAAT CGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCTAGATGGCACCACTGCACTTTAACC CAGGTGGAAAAGTGATACTCTGTTTTAAAATAAATAAATAAATAAAATGTATGGGTTTTT TGTTTTTTTGTTGTTGTTATTTTTGAGACAGTGTCTCCCTCTGTCACCCAGGCTGGAGTG CAGTGGTGTACTCATAGCTCACTGCAACCTCTGCCTCCTAGGCTCACGAGATCCTCCCAC CTCAGCCTCTCTAATAGCTGGGACTACAGGCATGGGTCACCACGCTTGGCTAATTTTTTA AGGTTTTGTAGAGACAGGGTCTCCCTATGTTGCTCAGGCTGGTCTTGAACTCCTGAGCTC AAGTGATCCTCCCACCTTGGTTTCCCAAAGTCCTGGAAAGTGCTGGAATTACAAACATGA ATCACTGTGCCTGGCCTAAAATGTATGTTTTTCTAAAAAAAAAAAAAAAAAAAAATCAGA GAATATAAATACTAAAAAACAAACATAGAAGTGCAGAAATATAAAGACTTAGTGTATAGA CCCTTAAAGCCCCCTAATTAACTCAGAGTCATGTGGCCTCACTGGCATTTCGATCTCGTT ATATACCTTCAATGCACTTTGCAGGCAACTCTCATATTTTTCTGATGAAAAGCAATTGCT CCTTTTTAGCCCCTTCGCTAAGATTTATTTGCAGGTGTCTCTCATTTTCTACTCCTTTTT AGAGCTTAGATGCCAGATGCCTTTTTAGGTTATTGAATGATAAAGTGCTTCTATCACTCT CCCCACCCAAAACCTGGGTGTGTAAACACCTGATTCAGAATTTCTCACTTCTCTATGTTT TATGGGTTGACTCATCACTTGGGTCCTCTCCTACCTCCAGGAAAATGGTTTTACTTTGAA CTGCTTTGTAATACCGAGATAACTTAAGCATGCATTGAGGCTCAAGGGCAGGGAGGTGGA TTCCATCACAGCATGAAATACTGAAATACAACTACACAAAACCAGTCTCCATTACCCAAT TCAGAAAGTGGAAAAGCTAAGCCTTGTTCTAATTTCTGTTCAGGTACTACTTAGTGGGCG TGCAGGAGCAGCAATGCGTTGATGGGGAGTGGAGCAGTGCACTTCCAGTCTGCAAGTTGA TCCAGGAAGCTCCCAAACCAGAGTGTGAGAAGGCACTTGTAAGTAGGAGGCTCATATCTG TCTTGTTCACAGCTGGATCTCCAGGGCCTGGCATCACTCCTGGCATATGCTCAGTATATA TCTGTTTAATGTGGGACATTTTGCTTTTGAATGGGTTGGCCTTGGCCTGGCTGTAGAAGG GACTCATAAACTATTAACTCACATTTTTATAAATGGAAGTTGGAAGTTCCCATTCACTAC CATCATCACAAATACCTCATGAGACCCTGTTGGTAGAAGTTGTTGTCTCATGTGCCTTAT AGAGCAGTGGTTCCCAACCTTTTTGGCACCAGGGATGGGTATCATGGAAGATGACTTTTC CACGGATGGGGGTGGGGAGAGTGGGGATGGTTTGGGGATGATTCAGATGCATTACATTTA TTGTGTACTTTATTTCTATTATTATTACATTGTAATATATAATAAAATGATTATATAACT CACCATAATGTAGAATCAGTGGGAGCCCTGAGCTTGTTTTCCTGCAACTAGAGGGTCCCA TCTAGTTAGGAGTGATGGGAAACTGACAGATTATCAGGCATTAGATTCTCATCTGGGAGT GTTGGGAAACAGTGACAGATCATCAGGCATTAGATTCTCATCTGGGAGTGATGAGAGACA GTGACAGATCATCACACATTAGAATCTCATCTGGGAATGATGAGAGACAGTGACAGATCA TCAGGCATTAGAATCTCATCTGGGAGTGATGGGAGACAGTGACAGATCATCAGGCATTAG ATTCTCATCTGGGAGTGATGGGAGACAGTGACAGATCATCAGGCATTAGATTCTCATCTG GGAGTGATGGGAGACAGTGACAGATCATCAGGCATTAGATTCTCATCTGGGAGTGATGGG AGACAGTGACAGATCATCAGGCACTAGATTCTCATCTGGGAGTGATGGGAGACAGTGACA GGTTACCAGGCATTAGACTCTCATAAAGAGGGGTCAACCTAGATCCCTCGCATGAGCAGT TCACAATAGGTTTCACGCTCTTATGAGAATCTAATGCCACCTCTGACCTGACAGGAGGTG GAGCTCAGGCAGCAATGTGAGCAAAGCAGAGTGGCTATAAATACAGCTGAAGCTTTGCTT GCCTGCCCGCTGCTCACTTTCTGCTGTGTGGCCCAGTTCCTAATAGTCCGTGGACCGGTA CCGGTCTGTGGCCCTGGGGTTGGGGATCCCTGTTATAGAGCAAAGCACATAAGCACAATG CGTGAGAATTGGAAAAGTCTCTAAAATTCTTCTAGGCTCCAAAACTAAACAAACAACACT GAACAGATCCATTTTCATTGAGATTCTTCTTTTAGTTCATATTTATTACTGGGATAATAT TAATAAGTATATTTAAGCCAGAAAATATAAATGATTTGCCATGTTGAAAACCCAAATCTT TACTTAAGCTAGCCTGGTTCTGAGCCCCCATTCAGAGAGCTAACTGCTGCTCACTGGCTT CAGAGTATATAGCTGGGTCTCAGTCCTTATGTTGTAACTTGTGAAAAATTTTCTTTCTTC AGCTTGCCTTTCAGGAGAGTAAGAACCTCTGCGAAGCCATGGAGAACTTTATGCAACAAT TAAAGGAAAGTGGCATGACAATGGAGGAGCTAAAATATTCTCTGGAGCTGAAGAAAGCTG AGTTGAAGGCAAAATTGTTGTAACACTACAGCTGAGCAGATGTAATAGAAATAAACCTAT GAATAAATTTTCTTCTTGGTTCTGAAA OMIM ID 120831