| Entrez gene ID | | 7289 |
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| Official gene symbol | | TULP3 |
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| Full name | | tubby like protein 3 |
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| Aliases | | ,MGC45295,TUBL3, |
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| Gene summary | | This gene encodes a member of the tubby gene family of bipartite transcription factors. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region. The encoded protein binds to phosphoinositides in the plasma membrane via its C-terminal region and probably functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis, for instance, induced by G-protein-coupled-receptor signaling. It plays an important role in neuronal development and function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 12 Locus: 12p13.3 |
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| Gene position | | 3000033 - 3050306 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 50274 bp |
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| Gene sequence |
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| OMIM ID | | 604730 |
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