Entrez gene ID | | 7307 |
Official gene symbol | | U2AF1 |
Full name | | U2 small nuclear RNA auxiliary factor 1 |
Aliases | | ,DKFZp313J1712,FP793,RN,RNU2AF1,U2AF35,U2AFBP, |
Gene summary | | This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q22.3 |
Gene position | | 44527688 - 44513066 Map Viewer |
Gene orientation | | minus |
Gene size | | 14623 bp |
Gene sequence |
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OMIM ID | | 191317 |