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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBE2B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7320
Official gene symbolUBE2B
Full nameubiquitin-conjugating enzyme E2B (RAD6 homolog)
Aliases,E2-17kDa,HHR6B,HR6B,RAD6B,UBC2,
Gene summaryThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q23-q31
Gene position133706870 - 133727799  Map Viewer
Gene orientationplus
Gene size20930 bp
Gene sequence
OMIM ID179095