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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBE2D2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7322
Official gene symbolUBE2D2
Full nameubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
Aliases,E2(17)KB2,PUBC1,UBC4,UBC4/5,UBCH5B,
Gene summaryThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q31.2
Gene position138940751 - 139008019  Map Viewer
Gene orientationplus
Gene size67269 bp
Gene sequence
OMIM ID602962