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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBE2D3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7323
Official gene symbolUBE2D3
Full nameubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
Aliases,E2(17)KB3,MGC43926,MGC5416,UBC4/5,UBCH5C,
Gene summaryThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q24
Gene position103790032 - 103717133  Map Viewer
Gene orientationminus
Gene size72900 bp
Gene sequence
OMIM ID602963