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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UBE2V1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7335
Official gene symbolUBE2V1
Full nameubiquitin-conjugating enzyme E2 variant 1
Aliases,CIR1,CROC-1,CROC1,UBE2V,UEV-1,UEV1,UEV1A,
Gene summaryUbiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.2
Gene position48732494 - 48697661  Map Viewer
Gene orientationminus
Gene size34834 bp
Gene sequence
OMIM ID602995