Entrez gene ID | | 7341 |
Official gene symbol | | SUMO1 |
Full name | | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) |
Aliases | | ,DAP1,GMP1,OFC10,PIC1,SENP2,SMT3,SMT3C,SMT3H3,UBL1, |
Gene summary | | This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q33 |
Gene position | | 203103322 - 203070903 Map Viewer |
Gene orientation | | minus |
Gene size | | 32420 bp |
Gene sequence |
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OMIM ID | | 601912 |
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