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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UFD1L (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7353
Official gene symbolUFD1L
Full nameubiquitin fusion degradation 1 like (yeast)
Aliases,UFD1,
Gene summaryThe protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.21
Gene position19466738 - 19437464  Map Viewer
Gene orientationminus
Gene size29275 bp
Gene sequence
OMIM ID601754