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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UGDH (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7358
Official gene symbolUGDH
Full nameUDP-glucose 6-dehydrogenase
Aliases,GDH,UDP-GlcDH,UDPGDH,UGD,
Gene summaryThe protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
LocationChromosome: 4   Locus: 4p15.1
Gene position39529218 - 39500375  Map Viewer
Gene orientationminus
Gene size28844 bp
Gene sequence
OMIM ID603370