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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL49 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 740 Official gene symbol MRPL49 Full name mitochondrial ribosomal protein L49 Aliases ,C11orf4,L49mt,MGC10656,NOF,NOF1, Gene summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for the HRD1 protein use in their respective 3' UTRs some of the same genomic sequence. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq] Location Chromosome: 11   Locus: 11q13 Gene position 64889728 - 64894841  Map Viewer Gene orientation plus Gene size 5114 bp Gene sequence >MRPL49:10195523..10200636:Length=5114 GCACCGGCGAACCTGCCTGGGCAGGCAGCTCGCGCAGGACGGGGCGGGACCAGACAGTTG CGCGCACAGAAGGCTGGCGTAGCAGGTAAAGATGGCAGCTACCATGTTCCGGGCTACGCT GCGGGGATGGAGAACCGGTGTCCAGCGGGGCTGCGGGCTACGGCTGTTGGTGAGAGCGCT GAGCGAGGAGCTGAGGGCATCGCGTGGGTGTGAGGCTCAGTGTTAATCATTGTTAACCCC GAAAACTAAGGCATTCCTACTTGGGGCCTTAGTTTTGCCGTTTTCGATCAGGAGAACTTG TCCCGAGTGTACATATAGAATCGAGAGGGAAAATGGTAGACTGGGGTGCTCTTTGGGAGC ACTTAACACAGTGCCTGGCAGTGTCTATATAAGCCACAACGTTTCAGGTAAGGGGCGGGG TCCTAGCATATGAGTGTGCGTGGGGAATTATGATTGCCTTAATTCTTTTTTTTTTTTTTT TTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGGGCAGTGGCGCGATCTCGGCCCAC TGCAAGCTCCGCCTCCCAGATTCACGCCATCCTCCTGCCTCAGCCTCCCGAGTAGCTGGG ACTACAGGCTCCCGCCACCATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTT TCACCTTGTTAGCCAGGATGGACTGGATCTTCTGACCTCGTGATCCGCCCGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGCCGCCGAACCCGTCTGATTGCCTTAATTCTTA AGGCAATCATAAGATTAAACATCACTATATCCCGTCACAGATGTGATTAGGTTAGCAAGG CCAGCCAGGCAATCATGGAGGTACAAACAAGGCCACGCTGCCAATATAATAATATCTATT TCTAAAACCGAGACAGAAAGTTAAGCCTTAAGTTTCTAAAGGCTTGATTGACTTTTCAGA AGTGTACATATACTCTTTTGCATCCCACAGAAATCCTGAGAGGCAGACCATTCAGAGTAC CTGAGCCTCCTTTCCATCCCATCTGTACCCTGCACCATGGAAAACCAAAGACTGGTGCTA TCTTATGTCAACCTAAATAACAGACTCTAAAAGAAAAGGATATTTATTCGGGAATGGGTA TAGACTATGTGCTTATCAGGGAGGTAAAAGAAGACAAAGGTTTTTAACAGAAAAATGGGC CAGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGCGTAGATCA CCTGGAGTCAGGAGTTTGAGACAAGCCTGGCCAACATGGTGAAACCCGTCTCTAGAAAAA ATACAAAAATTAGCCGGGTGTGATGGCGTGTGCCTGTAGTCCCAGCTACTTGGGAGGCTG AGGTAGGAGACTTGCTTGAACTTGGGAGGCGGAGGTTGCAGTGAGCCGAGATCACACCAC TGCACTCCAGCCTAGGTGACAGAGTGAGACTCTATCTAAAAAAATAATAAAAATAAATAA AGGAAAGGAAAAATGAGTATTACATAATTGTTTTGAGACAGTTATCCTTGGCTACAAGGA TGAATAACATGGGTGGTGCCAGTTCAAGATTGGACAGGCAGTTGTTGGACAGATGGCCAT GCAGGAATTTGTTTTCTTTTGTTTTGTTTGAGAGAGTCTCGTCGCTCTGTCACCGAGGCT GGAGTGCAATGGTGCGATCTTAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTC TCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCATGCCCGGCTAAT TTTTGTATTTTCAGTAGAGATGGGGTTTCGCCATGTTGGCCAGGCTGGTGTTGAACTCCT GACCTTAGATGATCCTCCTGCCTCAGCCTCCAAGGTGCTGGGATTACAGGCGTGAGCCAC CTTGCCCAGCCAGAAATATTTTTTTGTGTAAGGTTGAAGTGGCCTTTGTGCAAGGCTGTG GTTTTTGCAGTCTTTTGTGGTAGTTCTTGTTATTAAGTATTTGTGCCCAAGAACTCTCTC TTCGTGGCCCTCCCTAGCTCTATTTGTTGGGATTTTTAACCCAAGTGACTCACTCCATTT TGATTCTGATAGCTTTCACACCGTCGCCCAGCCTTTTATTTATGTCATTCTCTCTGCCTG TAATGTTTCCATTCTCTACTTACTGAAGTTATGCCATCCTGTGTTGGGTAGGCTAATGGA GAAATGGGATTTTTGTTTTGCTTCAGAGCCAGACCCAGGGCCCTCCAGATTACCCCAGGT TTGTGGAGTCTGTGGATGAATATCAGTTTGTGGAGCGCCTGTTACCGGCTACCAGGATCC CAGATCCCCCAAAGCATGAACATTATCCTACCCCTAGTGGCTGGCAGCCTCCCAGAGGTG AGCTGGGTGGTTAGGGATGATTTGAAAGCTTCACGGAGCATCACCTCCTCCCCAGAGGTT GGCCTCCCCCATGAGGCTCTGGACTCTCCAGTGGGTTCAGGACTCATTTTGCAATCCCTC TGGGTTACATCTGTCTCATGCCCAAGGAAGAGCCGAGGAGTGGAGCCTTCTGTTGTTCAC TGGTACTCATCCATCCACACTATTGAGATCAGGTCTTCCCCATATGGGGGAAAGTAAACA ACAGAGAGAAAACCCAAGAGCTTGGACCTTCTTTCCCCCCAGCAGACTATGTACTGTAAT TAAGAACACAGCTTGGAGTCAGGCAGTTCTGGGTTTGAATTTGGCTTTATTTACTGTTGA TGTTATCTTGAATTAGTCACTTAGCTTGACCCAACCTGTTTTAGCAAAATGGAGATAATC TGCTCAGTACATAGAGCCCTTAGTGCAGAGCCCAGCATATGGTAGGTGCTCAGTGCTTGC AAATCCCAATCTCTTTGTTCCAGAGATTGATTTCGGCCTCCCTGACCCAGTGGAGGAGGG CAAGGGTTGGCCTAGAGGGGGACCCAAAGATCCAGGGAGGCATGTCCCTGATTTCATTTT TTCTTGAGCACCTACTTAGTGCCAGGCCCTGTGTGGGGCCTTAGGGTACCAGGGTGAACA ATTTGGTCCTGACTCCAAGCTGAAGGAAAGAGGAGACCCCCTGACCTAAAGTCTGGAGGT GGCTTGGTCCAGCTGGGTGCACTGGCCCTCTGCAGACTGAGAGCAAGGGCCTTGGCTGAG GTGGGATGGCACGTAGGAAGAGTTGATTTAACAGTGTCTTTCCCTGTTGCAGACCCCCCA CCCAACCTGCCTTACTTTGTACGACGCTCTCGGATGCACAACATCCCCGTCTACAAGGAC ATCACGCATGGCAACCGGCAGATGACTGTGATCCGGAAAGTGGAAGGGGACATCTGGGTA AGTGGGTGGGTGGGTCTGGGACTGGGCCTGACCCTTTCAGGGCTGAAGGGACAGGAGTCT TTTTAAGGGAAGGGACTCTTGGCCTGACCTGATTTGTCATCTTTCCCCAGGCCCTGCAGA AAGACGTGGAAGATTTTCTGAGCCCGCTGCTGGGGAAGACACCTGTCACCCAGGTCAATG AGGTGACAGGTACCCTACGGATCAAGGGCTACTTTGACCAGGAGCTTAAAGCCTGGCTCT TGGAGAAAGGCTTCTGAGGCCCAGCCGAGCAGCCTGCTTGTCAGCATGCCCTGTGGATCA AGTCTAGGGGGCCTCAGGAGGAGGGAGGTGGGTGTTGGAGCCCCTGAGACAGGGGATACA GAAACTAGGGCTAAAGGACTTTGGGGTCAGGCCTTGCTTGCATAAAGGAGAAAACAACTC TATGTACATGCTGGGGGAGAGTGCCTAATGTGGGAGACCAAATAGGGATCACCAGGCTAA TGGGGGGCGTCAGCAGCTTTCTCTCCCTCCTATCTTGGCCTGTTCTTTTTTGTTTTTTGA GACGGAGTCTCACTCTGTTGCCCAGGGTGGAGTGCAGTGGCATGATCTTGGCTCACTGCA ACTTCCACCTCTGGGATCAAGGGATTCTCCTGCCTCAGCCTCTTGAGTAGCTGGGATTAC AGGCGCCCACCACCACAGCCTGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCA TGTTGGCCAGGCTGGTCTCAAACTCCTGACTCGAAGTGATCCGCCCACCTTGGCCTCCCA AAGCGTTGGGATTATAGGCATGAGCCATGTGCCTGGTCCACCTTGGCCTGTTTTGTTTTT CTTTCCTTGGGCTCAGCAATTCAAATTCTAGTTGTTATTTGGTGGAAGCAGTAGCCCAAC CCCAGTTTAGGGGAAGGTAGCACAGGGCAGAGCCACTGGGCACTTTGTTTCCTTGGCCCT CCGAAGCTCACTGTTGCAAATACCCCCAAGCCTTTGCTCTAGGCCAGATCTTGTTTGGTG CAGGTGATGGAGAACACAGATGACTCGGGCATGGGTCTTGGAGATCTTCTGTTCAAAGTA CAGTGCTGGCACTGGGGCACAGAGTGCCCACGTTAGCCCCGGGCTCTGATAGAGAGGTAG GAGGCACGTTCTTGGTCACTGTTCCATTGCAGACCAGACTTGCTGGCCTGACCACAAGGG AGTGGCTGGGAACTCACAGCCAGCATAGGGACATCCCCCTGCAGCCTTCTGACCTGCAAT CAAGGCTGGGGAGGGGTTTGCAGGCAGGAATATGCTGACCTTTCACCCTGCCATCCCATC CCAACCCCAGCTCACTAGCCTTCATATATGCCTTATACTTGGAGTCACAGGGGCCAAAGG CCTGAGACCCCACCCTGCCCCCAAACTGGCTAAGACAGCTTTCAGTTCCTGACTCCCCAA CTTGGTCTCTGCCCTGAAGCAGGGCACTGAACTCTGGGCTGCTTCTCTGTGTGTAAAATG GGCACATCTTCCTAATCTGTTAATGGTCAGTGGTGTCCCCAAGGATAGTGCTGGCTTCCA TGGAAACCCTCACTCCTGGAGATTCCATTCCATTTTCAAGTGTACAGCCACAGCAAGGAG CCCGACACTGATTTGATCGATTCTGTGACACAAACCCCACCAATTGTTAATGCAAGTTTT TATTTGGCTGTATATACAATTTAAGCTATTAAAATTTGTACAATATTTACAAATTAAATA ATCATCTGAAACTG OMIM ID 606866