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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UTRN (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7402
Official gene symbolUTRN
Full nameutrophin
Aliases,DMDL,DRP,DRP1,FLJ23678,
Gene summaryThis gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q24
Gene position144612873 - 145174170  Map Viewer
Gene orientationplus
Gene size561298 bp
Gene sequence
OMIM ID128240