Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for UVRAG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7405
Official gene symbolUVRAG
Full nameUV radiation resistance associated gene
Aliases,DHTX,p63,
Gene summaryThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13.5
Gene position75526212 - 75855282  Map Viewer
Gene orientationplus
Gene size329071 bp
Gene sequence
OMIM ID602493