Entrez gene ID | | 7430 |
Official gene symbol | | EZR |
Full name | | ezrin |
Aliases | | ,CVIL,CVL,DKFZp762H157,FLJ26216,MGC1584,VIL2, |
Gene summary | | The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6q25.2-q26 |
Gene position | | 159240456 - 159186773 Map Viewer |
Gene orientation | | minus |
Gene size | | 53684 bp |
Gene sequence |
| |
OMIM ID | | 123900 |
|