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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for VIM (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7431
Official gene symbolVIM
Full namevimentin
Aliases,FLJ36605,
Gene summaryThis gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
LocationChromosome: 10   Locus: 10p13
Gene position17270258 - 17279592  Map Viewer
Gene orientationplus
Gene size9335 bp
Gene sequence
OMIM ID193060