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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for WNT1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7471 Official gene symbol WNT1 Full name wingless-type MMTV integration site family, member 1 Aliases ,INT1, Gene summary The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq] Location Chromosome: 12   Locus: 12q13 Gene position 49372236 - 49376396  Map Viewer Gene orientation plus Gene size 4161 bp Gene sequence >WNT1:11515542..11519702:Length=4161 GCGGTGCCGCCCGCCGTGGCCGCCTCAGCCCACCAGCCGGGACCGCGAGCCATGCTGTCC GCCGCCCGCCCCCAGGGTTGTTAAAGCCAGACTGCGAACTCTCGCCACTGCCGCCACCGC CGCGTCCCGTCCCACCGTCGCGGGCAACAACCAAAGTCGCCGCAACTGCAGCACAGAGCG GGCAAAGCCAGGCAGGCCATGGGGCTCTGGGCGCTGTTGCCTGGCTGGGTTTCTGCTACG CTGCTGCTGGCGCTGGCCGCTCTGCCCGCAGCCCTGGCTGCCAACAGCAGTGGCCGATGG TGGTAAGTGAGCTGGTGCGGGGTCGCCACTTGTCCCGCGGCACAGAGCCAGGGGCCAACC CTACCCAGCTCCCACGCTCTGGGATCCGTCTGCCGACAGGCTCCCTCCCCGCTCTGACTT CCCTCCGCGACACCGAAGGGCGATCTGGCATGAAACTGCCCCAGACTCCAGCTCTGTACA AGTGGGGCGAATGATCCGCCCGCGGAGGCCTAAGATACCCCAGGCAGGGAGCCCACTCTC ATCTAGCACCGCCCTTCCCCTTTGAGCGCCAACTCCAGCCTCACGGCGGTGGCTCACCAC AGGTTTCCCCACCTCGGGAAGTGAAGGGCCAGGAGTTCGCCTAGAAAGGAGGGGAGAAGA GGGTGGGACTCCTAAGCATTTCACGCCTTGGGTGGGCAAGAACTGCAGGCCATGATTATC TCGCTCAGGCTGACCGGAAGAGGCTCGGAGATCCAAGGTAGACACTCGGTCTCCGGGTAC CTCCTCTGTCCAGTCTCCGGACCTAGGGCTCAGGCGAGCAGCCCTGGGACTACTGGGCAC ACACAAGTCTGGACGCCCAGTTCTTTCAAATTAGTGAGCCTGGGAGAGCGGGTATTATTA ATCTCCCGCCATTCTCTCCAGCCACATACCCCCAGGAAGAGGACCGGGTGGCACAGTTTT TATGGTTAGGGTGCGGATCCCCTTCCTGAGCCTGAGCTATCATACGTCCCACCAGGGGTA TTGTGAACGTAGCCTCCTCCACGAACCTGCTTACAGACTCCAAGAGTCTGCAACTGGTAC TCGAGCCCAGTCTGCAGCTGTTGAGCCGCAAACAGCGGCGTCTGATACGCCAAAATCCGG GGATCCTGCACAGCGTGAGTGGGGGGCTGCAGAGTGCCGTGCGCGAGTGCAAGTGGCAGT TCCGGAATCGCCGCTGGAACTGTCCCACTGCTCCAGGGCCCCACCTCTTCGGCAAGATCG TCAACCGAGGTGGGTGCCCAGGAAGGCGACGCTTCCGGGAGCAGGGGAAACGCGGGGTCA CCCCCAGGGCATGGGCGGGCGAGTTCAGAGAAGGTGTCCCAGGCGCCTGGAGGGTCACAC AATCAACCTTGCCAAGTGCCTCGTGCCCAGCGCCAGCTCGGGGCCAGACTTCTACCAGGC GTTTTCCAGCCGTGCACCCTGGAAACGAAGCTTAACTTTTCTGAGCTACTGCCCCAGATA AAGAAAGTTTCGGGTCGCGGACGCCGGCTGACCGCCGCTTTCCCCCAGCCTCTCTCAAAA GCGCCTGGGAAGCTGCTCTCTGCAGGCGTGTGTCTGGCCTCTCGCCCAGCAAGGCTTGCA CCGCCAAAATGGGCCGAAAGTTTTGGGCTGCGAAGAAGTCTTGGGGATGTATGGTTCTTC CGCTCCCCTCTCTTCGGTTTGTCTCTCTGGGGCTGCTCCACTTCCGCTATCGAGCCAAAA TGCGCCCTAGAATCTCCCAGTAAGGTGTGATTACGCCCGTGGACGTGGCTGCGTGCCCAC GCACCTGCTTTCTCTACTAGCCCTAGAGACCAGCTTTCCAGCACTGCCGGCCCTGGCTCT CAGGACTCAAAGTGCGGAGTCGGGGGTGGGATTCCGGTCCCAAGCCCTTCATGAGGGTGC TGGCCGCGCCCCGCGTACCCCCTCGCTGATCCCCGCTCCCTTCTCCCACAGGCTGTCGAG AAACGGCGTTTATCTTCGCTATCACCTCCGCCGGGGTCACCCATTCGGTGGCGCGCTCCT GCTCAGAAGGTTCCATCGAATCCTGCACGTGTGACTACCGGCGGCGCGGCCCCGGGGGCC CCGACTGGCACTGGGGGGGCTGCAGCGACAACATTGACTTCGGCCGCCTCTTCGGCCGGG AGTTCGTGGACTCCGGGGAGAAGGGGCGGGACCTGCGCTTCCTCATGAACCTTCACAACA ACGAGGCAGGCCGTACGGTGAGCTTTGAGAGGCTCCGCACCCTAAGCGGAGCGGCAGGGG CCAACCTCGGGCTGGGGAAGTGACGGTCGGTGAGATAAGGCAAGGGGCACCAGGAGAGGG CGTCCTGGGAGAGCCGGAGGCTTGGAACGAAGACGGAGAATAGAGGAGACAGTGGCTGAG GGCAAAGGTATGTCTGGCCCGCGGACAGGTAGAAGAGGTTGCAAATCAAGCACAGTCTCT TCGCTGTACAGATTCGAAAAATAAGCCTGAGAGGCCGAGACTGACTCGCCGCGGCGGAGC AGGGTTGGGCAGGGTTTCCAAATCTCAGCGGAACATTTCGCGCCTCCCTTCCCCTGGGCT CAGCTAGGCCTGGGCCTTTGCTGAGGTCCGGCCCCCGTGGCGTCCGGGAGAGGGCAGTGT CTGGGAGGGTGACTCTGGCCCGGTGCCCTGGGACACTCTTTCTTCCCCTATCCCCGCAGA CCGTATTCTCCGAGATGCGCCAGGAGTGCAAGTGCCACGGGATGTCCGGCTCATGCACGG TGCGCACGTGCTGGATGCGGCTGCCCACGCTGCGCGCCGTGGGCGATGTGCTGCGCGACC GCTTCGACGGCGCCTCGCGCGTCCTGTACGGCAACCGCGGCAGCAACCGCGCTTCGCGGG CGGAGCTGCTGCGCCTGGAGCCGGAAGACCCGGCCCACAAACCGCCCTCCCCCCACGACC TCGTCTACTTCGAGAAATCGCCCAACTTCTGCACGTACAGCGGACGCCTGGGCACAGCAG GCACGGCAGGGCGCGCCTGTAACAGCTCGTCGCCCGCGCTGGACGGCTGCGAGCTGCTCT GCTGCGGCAGGGGCCACCGCACGCGCACGCAGCGCGTCACCGAGCGCTGCAACTGCACCT TCCACTGGTGCTGCCACGTCAGCTGCCGCAACTGCACGCACACGCGCGTACTGCACGAGT GTCTGTGAGGCGCTGCGCGGACTCGCCCCCAGGAACGCTCTCCTCGAGCCCTCCCCCAAA CAGACTCGCTAGCACTCAAGACCCGGTTATTCGCCCACCCGAGTACCTCCAGTCACACTC CCCGCGGTTCATACGCATCCCATCTCTCCCACTTCCTCCTACCTGGGGACTCCTCAAACC ACTTGCCTGGGGCGGCATGAACCCTCTTGCCATCCTGATGGACCTGCCCCGGACCTACCT CCCTCCCTCTCCGCGGGAGACCCCTTGTTGCACTGCCCCCTGCTTGGCCAGGAGGTGAGA GAAGGATGGGTCCCCTCCGCCATGGGGTCGGCTCCTGATGGTGTCATTCTGCCTGCTCCA TCGCGCCAGCGACCTCTCTGCCTCTCTTCTTCCCCTTTGTCCTGCGTTTTCTCCGGGTCC TCCTAAGTCCCTTCCTATTCTCCTGCCATGGGTGCAGACCCTGAACCCACACCTGGGCAT CAGGGCCTTTCTCCTCCCCACCTGTAGCTGAAGCAGGAGGTTACAGGGCAAAAGGGCAGC TGTGATGATGTGGAAATGAGGTTGGGGGAACCAGCAGAAATGCCCCCATTCTCCCAGTCT CTGTCGTGGAGCCATTGAACAGCTGTGAGCCATGCCTCCCTGGGCCACCTCCTACCCCTT CCTGTCCTGCCTCCTCATCAGTGTGTAAATAATTTGCACTGAAACGTGGATACAGAGCCA CGAGTTTGGATGTTGTAAATAAAACTATTTATTGTGCTGGGTCCCAGCCTGGTTTGCAAA GACCACCTCCAACCCAACCCAATCCCTCTCCACTCTTCTCTCCTTTCTCCCTGCAGCCTT TTCTGGTCCCTCTTCTCTCCTCAGTTTCTCAAAGATGCGTTTGCCTCCTGGAATCAGTAT TTCCTTCCACTGTAGCTATTAGCGGCTCCTCGCCCCCACCAGTGTAGCATCTTCCTCTGC AGAATAAAATCTCTATTTTTA OMIM ID 164820