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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for XDH (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7498
Official gene symbolXDH
Full namexanthine dehydrogenase
Aliases,XO,XOR,
Gene summaryXanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p23.1
Gene position31637611 - 31557188  Map Viewer
Gene orientationminus
Gene size80424 bp
Gene sequence
OMIM ID607633