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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for YWHAZ (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7534
Official gene symbolYWHAZ
Full nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Aliases,14-3-3-zeta,KCIP-1,MGC111427,MGC126532,MGC138156,
Gene summaryThis gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q23.1
Gene position101965623 - 101930804  Map Viewer
Gene orientationminus
Gene size34820 bp
Gene sequence
OMIM ID601288