Entrez gene ID | | 7534 |
Official gene symbol | | YWHAZ |
Full name | | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide |
Aliases | | ,14-3-3-zeta,KCIP-1,MGC111427,MGC126532,MGC138156, |
Gene summary | | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q23.1 |
Gene position | | 101965623 - 101930804 Map Viewer |
Gene orientation | | minus |
Gene size | | 34820 bp |
Gene sequence |
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OMIM ID | | 601288 |
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