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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTTG1IP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID754
Official gene symbolPTTG1IP
Full namepituitary tumor-transforming 1 interacting protein
Aliases,C21orf1,C21orf3,PBF,
Gene summaryThe encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1. [provided by RefSeq]
LocationChromosome: 21   Locus: 21q22.3
Gene position46293741 - 46269513  Map Viewer
Gene orientationminus
Gene size24229 bp
Gene sequence
OMIM ID603784