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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ZFX (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7543
Official gene symbolZFX
Full namezinc finger protein, X-linked
Aliases,-,
Gene summaryThis gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq]
LocationChromosome: X   Locus: Xp21.3
Gene position24167762 - 24234372  Map Viewer
Gene orientationplus
Gene size66611 bp
Gene sequence
OMIM ID314980