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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CA11 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 770 Official gene symbol CA11 Full name carbonic anhydrase XI Aliases ,CARPX1, Gene summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.3 Gene position 49149451 - 49141272  Map Viewer Gene orientation minus Gene size 8180 bp Gene sequence >CA11:complement(21409490..21417669):Length=8180 AAGGGACAAGAGAGAAGAGAGACTGAAACAGGGAGAAGAGGCAGGAGAGGAGGAGGTGGG GAGAGCACGAAGCTGGAGGCCGACACTGAGGGAGGGCGGGAGGAGGTGAAGAAGGAGAGA GGGGAGAAGAGGCAGGAGCTGGAAAGGAGAGAGGGAGGAGGAGGAGGAGATGCGGGATGG AGACCTGGAGTTAGGTGGCTTGGGAGAGCTTAATGAAAAGAGAACGGAGAGGAGGTGTGG GTTAGGAACCAAGAGGTAGCCCTGGGGGCAGCAGAAGGCTGAGAGGAGTAGGAAGATCAG GAGCTAGAGGGAGACTGGAGGGTTCCGGGAAAAGAGCAGAGGAAAGAGGAAAGACACAGA GAGACGGGAGAGAGAAGAAGAGTGGGTTTGAAGGGCGGATCTCAGTCCCTGGCTGCTTTG GCATTTGGGGAACTGGGACTCCCTGTGGGGAGGAGAGGAAAGCTGGAAGTCCTGGAGGGA CAGGGTCCCAGAAGGAGGGGACAGAGGAGCTGAGAGAGGGGGGCAGGGCGTTGGGCAGGG GTCCCTCGGAGGCCTCCTGGGGATGGGGGCTGCAGCTCGTCTGAGCGCCCCTCGAGCGCT GGTACTCTGGGCTGCACTGGGGGCAGCAGGTAAGACCTGGGGTTCCCGGGAGGAGCCCCC GAGGGAGGGTGGAGGTGGGGATGCCAAGGAGAGGGATTCAGGCTGCTCTCTTCCCAGCTC ACATCGGACCAGCACCTGACCCCGAGGACTGGTGGAGCTACAAGGATAATCTCCAGGGAA ACTTCGTGCCAGGTGCCGCCAAGGCGGGGACCCAGGAGTCCGGCCCTCCCGGCGCCTCCT TCTTCAGACTCAGGAACCTGGGTTCCCAGCTCCCTCCTCCCCCCCAGGACCAGGAGTCCC AGCCCCCTCCTCTGTCCCTCAGGAGTCGGGCCAGCTTCTGAACCCCAGGGGCTCACCATG GGACATTATACATGCGCATTTCAAGTAGTGAGTGGGAGTGAGTGGAAGGAAAGTGTGGGG GTGGAGATTATGTGTGTGTTTGCCGGGAGAGGAAGGTCCTGGCTCCTGCTAGGAACCAGA GGCTGGGTGGCCCCGTCCCCCACCTTGTCCAGCCTTCTCTTGCAGCTCCTCTCCCCAACA CATTAATAATAATCCAGCTGTGGGATAAGAGCGATTAAAAAAAAGAACTACAACTCCCAC GGGGCTCTGGGGCAGGTAGGCAGCAGAGGGGTAGGCTGGTAGCACTGGGGCCTGCTGGGA GTTGTAGTTCCATCTACAGTGGCTTAAGATGGGTTTGATCGGCTGGGCGCGGTGGCTCAC GCTTGAAATCCCAGCACTTTAGGAGGCCGAGGTGGGTGGATTACCTGTGGTCAGGAGTTC AAGACCAGCCTGGCCAACTTGGTGAAACCCGTCTCTGCTAAACTTGGAAACTATTCCAAG ATTCTTCTAGGACCCAGAATTCTGGATCTGAGCCCAGTCCTCCCTCAGACCCAGGAGTCT AGGTCCCTAGCCCCTCCTCCCCTGGGATCTGGGAGTCCAGACCACAGCCCACTCAGCAGA TACCAGCCCTGGGATCCAGTCTCTATTTCTGACTCCTTGTCCTCCTACTCCGACCCCACC CCCAGGGCCTCCTTTCTGGGGCCTGGTGAATGCAGCGTGGAGTCTGTGTGCTGTGGGGAA GCGGCAGAGCCCCGTGGATGTGGAGCTGAAGAGGGTTCTTTATGACCCCTTTCTGCCCCC ATTAAGGCTCAGCACTGGAGGAGAGAAGGTAAGGGGCTTGGAGGGAGGAGCTATTGAACC CACTGGGGATGGGCATGAATAGAGGCTGGGGAATGGGGTGCTGAGGTAGGAGAGCAGCCT TGGGGGAGGAGGGGACACCCAGTGGGTGGAGAGGAGGCTGCTTACACTGTAAAATGGATC ACCCATTCTTCCCATCCCAAGCATGGTCCCCTAGTCTCCCCATCTCTGCAGAAGCAATGA AAAGCAGAACATTTCCTGTGCCAGGCAGATTTAAAACCTTGATAAGCCTCTCATCTCATA ACCACCCCACAAAATGGGTACAATTATTATTATTGTTATTATTATTATTATTATTTTGAG ATGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGATGTGATCTCAGCTCACTGCA ACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCCCAGCCTCCCGAGTAGTTGGGATTA CAGGCATGCGCACCATCACGCCCAGCTAATTTTTTGTATTTTTAGCAGAGATGGGTTTTC TCCATTTTGGTCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCTGCCTCGGCCT CCCAAAGTGCTAGGATTACAGGCATGAGCCACTGCGTCCAGCCAAAATGGGTACAATTAT TAACCTTATTATATACATGCAGAAACTGACACACAGAGGTTAAGTTACTTGCCTAGGATC ACACAGAGAGCCAGCACTGGCATTCAAACCAAGCAGCGTAGCATGAATGCTGGGACCTGC TTTATAGTACCATGCTGGGAACCATACTTTTTTTTTTTTTTTTTGGAATTGGGATCTCAC TCTGTGACCCAGGCTGGAGTGCAGTGGCCCAGTCATAGCTCACTGTAACCTCAAATTCCT GGGCCCAAGTGATCTTCCTACCTCAGCCTCAAAAATAGCTAGGACATGCCTGGGTGTGGT GGTTCATGCCTGTAACCCCAGCACTTCGGGAGGCCGAGGTGGGTGGATCACGAGGTTAGG AGTTCGAGATCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATT AGCCGGGTGTGGTGGCATGTGCCTGTAATCCCAGCTACTTGAGAGGCTGAGGCAGGAGAA TTGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCTGACATCACGCCACTGGACTCCAGC CTGGGTGACAGAACAAGACTCCATCTCAGAAAGAAATAAATACAGAGAGAGAGGGAGAGA AAAGAAAGAGAGAGAGCGAGAAAGAAAGAGAGAAAGAGAGAAGGAAGGAAGGAAGGGAAG GAAGGAAAGGAAGGAAGAAGCCAGGACTGCAGGCACATGCCAGTATGCTTGGCTAACTTT TTAAGTTTTTTGTAGAGGTGGGGTCTCACTATGTTGTCCAGGCTGATGTCGAACTCCTGG GTTCAAGTGATCCTCCTTGCCTTGGCTTCCCAAGGTACTGGAATTACAGCTGTGATCCAC CGCGCCTGGCCAATACCATTTCTTATAAGAGCCGGCACTGCCTTTCATTTAGCTGCCCCA GCCAAAAGCCTCAAAGCCATTCCCCATCCTATCCTCTCTCCCTCATGTCCATTTCCAATC CATGTTCTTTCTAGCCTTGCTGCTAAATATTATTCAAATCCTTTCACCTATCACGCCCTC TACTGCCCCCAGTCTCATGTAGGCACCATCATCTCCCACCTGGACTGGTGGCGTACCCTC CTCACTGGCCTGCCTCTCAACTTCCTGCAATCTATTCACCCCACAGCTAGAGAGATGTTT AAAACACAAATAAGATCATATCACTCCTGCTCAAAATCCTCCTATTAGGATATGTAATAA CAGCAAACATTTACATAGCACTTACTATATGTTTGGCATTCTGGCAAATGTGTTATATAT ATGCAGTTTATTTATTTTTATTTTATTTTATTTTTTGAGTCGGAGTCTCGCTCTGTCGCC CAGGCTGGAGTGTAATGGAATGATCTCAGATCACTGCAACCTCCGCCTCCTAGGATCAAG CGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGCCCACCGCCACACCCA GCTGGTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAA ACTCCTGACCTCTGGTGATCTGCCCACCTCAGCTTCCCGAAGTGCTGGGATTACAGGCGT GAGCCACCACATCCAGCCTATATATGCAGTTTATTTAAATAAAAATACAAAACTCTCTAC TGTTTTCCACAAGGTCCTGCACCATTCAGCCCCCATAACCTCTCTCTCCTCTGTTCACTG GACTTTGATGAAGTCTCTTTGCTGTTACTCAAACAGGCCACCTCAGGGCCTTTGCACTTG CTGTTCCCTCTTCTTGGAATGCCCTTCTCTTTGTTCTTTTGCAAGTCACCCCTGCTTATC CTTCAGGTCCCCATTAAAATGTCACCTTTGGCCAGGTGCAGTGCTTCATGCGTGTAATTC CAGTATTTTTCAGAGGCTAAGGCAGGATGATGACTTGAGCCCAGGAATTTAAGACCAGCC TGGGCAACATAGGGAGAACCCTCTCTACCAAAAAAAAAAAAAAAAAAAAAAGAAAATTGA AAATTAGTTGGGCATGGTGGTATGTGACTGTGGTCCCAGCTACTTGAGAGGCTGAGGCAG GAGGATCGTTTGAGCCCAAGAGTTTGAGGCTGCAGTGAGCTGTGATGGCACCACTGCAAT CTAGCCTGGGTGCCAGAATGAGACTTTGTCTCAAAATAATAAATAAATAAAAATAAAATG TCACCTTTGCAGGGAAGCTTTTCCTGACATCCCCCATCTAAGCTGAGCTCCCCATGACAC CTCAGAGCTCCCAGTTCCCCCAAACATGAGCTCAGGATGTAGTTAATTAAGCAGTTACTT ATGTGATTCACAATTGTCTGTCTTGCCTTCATTAGAACATAAACTCCATAAGGCCCAGGA CTTTTGTCTACTTGTTTATTGCTCTATTCTTGCATCCACGGCACATAGCACCAGCTCAGT CAATATTTGTTAATCAAACAAATTCACCAATATTGGGCACCAACTTACAAACTGGCACAG AGCCTGGAAAGTGGTCAGTGTTCAAATTATGTTGAATGATTAAATTACTGTTGGAGGCCA GGCACGGTGGCTCACGCCTGTAACCCCAGCACTTTGGGAGGCCAAGGTGGGCAGAACACC TGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACACAGTGAAACCCTGTCTCTACTAAAAA TACAAAAATTGGCTGGGTGTGGTGGCACACACCTGTAGTCCCAGCTACTCGGGAGCCTGA GGGAGGAGAATCGCTTGAACCCAGGAGTCAGAGGTTGCAGTGAGGCGAGATCTCACCACT GCACTCCAGCCTCGGCAGCAGAGTGAGATTCTATTTAAAAAAAAAAAAAACAAAAACAAA AAGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGG ATCACGAGGTCCGGAGATCCAGACCATCCTGGTTAACACGGTGAAACCCCGTCTCTATTA AAAATACAAAAAATTAGCCGGGTGTGGTGGCGGGCGCCTGTAGTCCCAGCCACTCTGGAG GCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCGGAGCTCTCG CCACTGCACTCCAACCCGGGCGACAGAGCGAGACTCCGTCTCCCCCCAGAAAAAAAAAAA AGACCGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGG ATCACCAGAGGTCGGGAGTTTGAGACCAGCCTGACCAACGTGGAGAAACCCTGTCTCTAC TAAAAATAAAAAATTAGCCGGGCATGGTGGCGCATGCCTGTAATCCCAGCTACTCGGAAG GCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGGTTGCGGTGAGCCGAGATCACG CCACTGCACTCCAGCCTGGGCAACAAGAGCGAGACTCCGTTTCAAAAAAAAAAAAAAAAA AAAAAAAGACTGTTGGAATCAGAAAATGTAGGCGTGGGAAACGAGAGATAAAAGATCTCT CCCTGCCCCCTGACAGCTCCCGCCTCTCCCACAGCTCCGGGGAACCTTGTACAACACCGG CCGACATGTCTCCTTCCTGCCTGCACCCCGACCTGTGGTCAATGTGTCTGGAGGTCCCCT CCTTTACAGCCACCGACTCAGTGAACTGCGGCTGCTGTTTGGAGCTCGCGACGGAGCCGG CTCGGAACATCAGATCAACCACCAGGGCTTCTCTGCTGAGGTAGTGGCCACTGATTGTTT ACCCGCCACCCTCCGCCCTGAGTCACCCCAATTCCTCCCACCTCACCCTCTTAGTGTCTC ACCCCATCCTCCTCCACAGAACTGGCCTCCCACCCTAAGCACTAATCCTCAGCCTGATTC GGGCCCCCAAAGCTGGGGTCATGCTCTCCTCCCCTTCTGCTGGGGGACCCCATGCTCTGT GCTACCCCCAGGTGCAGCTCATTCACTTCAACCAGGAACTCTACGGGAATTTCAGCGCTG CCTCCCGCGGCCCCAATGGCCTGGCCATTCTCAGCCTCTTTGTCAACGTGAGCGGAGGCG AGATTCAGAGGGAGGGAGCAGTTGGGTGCCTGGAACCCGGGGTCTGAGGGAAGCGGGGTG CTGGGAGGCCCAGACTCCTGGGTCCTGGGGGAGGAGAAGGTTGAGGGCTTGGACTTCTGG GCTCCTGTGTCCTCACCTCGTACCCCCACACAGGTTGCCAGTACCTCTAACCCATTCCTC AGTCGCCTCCTTAACCGCGACACCATCACTCGCATCTCCTACAAGAGTAAGTCCCTGGCG TGCTGGGGGCAGTGGTCACACACGAGGGGGTTCAAGAGTGCCATCCCTCTTTACTCTGGC CTGATATTCCCGCAGATGATGCCTACTTTCTTCAAGACCTGAGCCTGGAGCTCCTGTTCC CTGAATCCTTCGGCTTCATCACCTATCAGGGCTCTCTCAGCACCCCGCCCTGCTCCGAGA CTGTCACCTGGATCCTCATTGACCGGGCCCTCAATATCACCTCCCTTCAGGTGACCCTCT GTCCGCACCGCCCTTCCTAGGCCTGGGTACTCCACTCACTGGCCTGGGCATCCCCTTGCT CACCTGCCCTCCCTCTCCTCATAGACTGAACTCAAGTAGGTAAGAGGGTCAGACCACCTT GGGGGTGGGTGGGGCTGAGAACAGACCCCGCCCACCTGCTCCCAGGGGCGGGGTTTCCTG CGTGACGTCACCAAGACCATTCACTATTCACTCCCAGTTTCCCACCCTCCTTCCACTGCA GATGCACTCCCTGAGACTCCTGAGCCAGAATCCTCCATCTCAGATCTTCCAGAGCCTCAG CGGTAACAGCCGGCCCCTGCAGCCCTTGGCCCACAGGGCACTGAGGGGCAACAGGGACCC CCGGCACCCCGAGAGGCGCTGCCGAGGCCCCAACTACCGCCTGCATGGTATGGTCCAGTC TGCACCCCCTCTAAGTCTTGGGCTAACCCTCTTATATGTGTCTCCCCTTGGTGTCTCAGT GTGATTCAGTCCCATCCTCCTTCCTGCGTCTATATGGTCTAGCCTCGTGAGCTGTCTCTT TTTCTCTCTTTCCCTACATGTCTATGTGGTACAGTCCACCTGCCAGCCCTAGGCCATTGC TAGCCCACGATTTGTCTTTCCTCTTCACTGCTTTGTAACTTGGTCTATAACCCTTGACCC CTGCCTTCCTATGGTCCAATTACCTACTGTTCTGTGCTTCCTATTACTGTGAATTTCCAA AATGGTACAATTTGGATCCTCTCTCCCTTTCCAAGTCGTACTACCTTACGCTGTTCCACA ATCTGATGCTCCCTTCCCCCTTACTGAGAATCTACAAGGTACAACCCCTTCCCTCCACCT CTGCCTCCCTGTGGTTTAGCCCAGGAATCTCACACACCCCCGGCTTCGCAACATGGTACA GTCCACACCCCCCCCCCCCCATGAAGACCTTCAAGTAGTTCAGCCTACTGCTGAATCTGG ACGTCCCGATTCCCCCCTCCTATTGGCTTCTTGTGGTTCAGCCCAGTGCTTCTCGACCTA GTACATTCTGGTTCCCCGCTCGCAGACTTCCGACGGTAGGGCCCAGCGCGGCGCAGCCCA CGCCCCCTGCACACCCCCCGCCCCTTCCATCCTATACTGACGCCCCCTGCCGTTGTTCTC TGTCTTACAGTGGATGGTGTCCCCCATGGTCGCTGAGACTCCCCTTCGAGGATTGCACCC GCCCGTCCTAAGCCTCCCCACAAGGCGAGGGGAGTTACCCCTAAAACAAAGCTATTAAAG GGACAGAATACTTCCTGTTT OMIM ID 604644