Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRIM25 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7706
Official gene symbolTRIM25
Full nametripartite motif-containing 25
Aliases,EFP,RNF147,Z147,ZNF147,
Gene summaryThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q23.2
Gene position54991409 - 54965270  Map Viewer
Gene orientationminus
Gene size26140 bp
Gene sequence
OMIM ID600453