Entrez gene ID | | 771 |
Official gene symbol | | CA12 |
Full name | | carbonic anhydrase XII |
Aliases | | ,CAXII,FLJ20151,HsT18816, |
Gene summary | | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q22 |
Gene position | | 63674075 - 63615730 Map Viewer |
Gene orientation | | minus |
Gene size | | 58346 bp |
Gene sequence |
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OMIM ID | | 603263 |
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