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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CACNA1C (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID775
Official gene symbolCACNA1C
Full namecalcium channel, voltage-dependent, L type, alpha 1C subunit
Aliases,CACH2,CACN2,CACNL1A1,CCHL1A1,CaV1.2,MGC120730,TS,
Gene summaryThis gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq]
LocationChromosome: 12   Locus: 12p13.3
Gene position2162416 - 2807115  Map Viewer
Gene orientationplus
Gene size644700 bp
Gene sequence
OMIM ID114205