Entrez gene ID | | 7803 |
Official gene symbol | | PTP4A1 |
Full name | | protein tyrosine phosphatase type IVA, member 1 |
Aliases | | ,DKFZp779M0721,HH72,PRL-1,PRL1,PTP(CAAX1),PTPCAAX1, |
Gene summary | | The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6q12 |
Gene position | | 64281920 - 64293489 Map Viewer |
Gene orientation | | plus |
Gene size | | 11570 bp |
Gene sequence |
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OMIM ID | | 601585 |
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