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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTP4A1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7803
Official gene symbolPTP4A1
Full nameprotein tyrosine phosphatase type IVA, member 1
Aliases,DKFZp779M0721,HH72,PRL-1,PRL1,PTP(CAAX1),PTPCAAX1,
Gene summaryThe protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q12
Gene position64281920 - 64293489  Map Viewer
Gene orientationplus
Gene size11570 bp
Gene sequence
OMIM ID601585