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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RNF103 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7844
Official gene symbolRNF103
Full namering finger protein 103
Aliases,KF1,MGC102815,MGC41857,ZFP103,hkf-1,
Gene summaryThe protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream VPS24 (vacuolar protein sorting 24 homolog) gene. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p11.2
Gene position86850978 - 86830516  Map Viewer
Gene orientationminus
Gene size20463 bp
Gene sequence
OMIM ID602507