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Gene information for IL1R2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID7850
Official gene symbolIL1R2
Full nameinterleukin 1 receptor, type II
Aliases,CD121b,IL1RB,MGC47725,
Gene summaryThe protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q12-q22
Gene position102608306 - 102644885  Map Viewer
Gene orientationplus
Gene size36580 bp
Gene sequence
OMIM ID147811