Entrez gene ID | | 7850 |
Official gene symbol | | IL1R2 |
Full name | | interleukin 1 receptor, type II |
Aliases | | ,CD121b,IL1RB,MGC47725, |
Gene summary | | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q12-q22 |
Gene position | | 102608306 - 102644885 Map Viewer |
Gene orientation | | plus |
Gene size | | 36580 bp |
Gene sequence |
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OMIM ID | | 147811 |
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