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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL57 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 78988 Official gene symbol MRPL57 Full name mitochondrial ribosomal protein 63 Aliases ,MRP63,bMRP63, Gene summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein which belongs to an undetermined ribosomal subunit and which seems to be specific to animal mitoribosomes. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 3p, 5q, 8q, 14q, and Y. [provided by RefSeq] Location Chromosome: 13   Locus: 13q12.11 Gene position 21750372 - 21753223  Map Viewer Gene orientation plus Gene size 2852 bp Gene sequence >MRP63:2730372..2733223:Length=2852 GCAGCACCCGCCCTGCGCCTCGGTGGCAGCCGTCCACGCCGTCAGTGCCTGGCGGTTCCC GTGGGACATACCGTCCACTCGCCACGCCCCTCCGCCCGCGGCGCACCCCACGCACCGTGC CCTGGCCGCCCGCCTCACGCACCGCTTTCCTCTCCGTCCAGCGCTCGCTGCAGCCGGGCC GTCTCGCAGTCCAGCGTGCTGGCCAGAGACCGCAGCTTCCCGCAGAAGCTCCGGATAGGG TCCATGCTGAGCACAGCGGGGAAGGACTCCAGGCGTACGCAGACCCCACCGCTCAGCTCA CAGCCTCCCGCCACTAGTTTGAATCTCGGCGCCGGACGCGTCCTCGGCTCTGCGCAGGCG CAGTCCTCTCTCGCGAGAGCCGAAGTCTCTCGCCGAGGCCCCAGGAGACCCCGCGAGACG GGTGCGCTTACGCCACGGCGTCTGCTGGCGGCCGCGGAGACGCAGAGTCTTGAGCAGCGC GGCAGGTGAGTAGCTGTGCGAATTCGGTTCTCTAGGGAGCTCCTTCTTCGCCTGCTGGCC TTACCTGGGCTCCCCGCTTCTCTGGAGGGGAGGCGGTGCGGGAACTCCCGTAGGCGTGAG CTGGAGCGCGCGCCCGCTGCTCTCTCCAGGTCCGGCCGCGCCAGTTCGCCTCCGCAAAGC CCGTCCCTCTCTTCCGCAGGCACCATGTTCCTGACTGCGCTCCTCTGGCGCGGCCGCATT CCCGGCCGTCAGTGGATCGGGAAGCACCGGCGGCCGCGGTTCGTGTCGTTGCGCGCCAAG CAGAACATGATCCGCCGCCTGGAGATCGAGGCGGAGAACCATTACTGGCTGAGCATGCCC TACATGACCCGGGAGCAGGAGCGCGGCCACGCCGCGGTGCGCAGGAGGGAGGCCTTCGAG GCCATAAAGGCGGCCGCCACTTCCAAGTTCCCCCCGCATAGATTCATTGCGGACCAGCTC GACCATCTCAATGTCACCAAGAAATGGTCCTAATCCTGAGTCGTCACCCTTGGATTTTAT GGATCACGGAGCTGACCATCTTTACCTGGTCCTGGAACTGAAAAACTGTAGCTTGTGTGA AAATGAGCCTTTGGACCAGTCTTTATTAAAACAAACAAACATGAGTAGTCTGCATATCGA ATATCTAGAGCTCTAAACCCCCAATACTTAAAAGTCTAATTGCTGTCCTGTGGTTTCATT AGTCTGATAGGAAGATAGGGATTTCCTCAGTCACAGATGATATTTTGAAGGAAAGCTGCA ATAAAGCCACAATGATTTGAGGTCTTTGCTTAAGTATGAGATACTTGATGGGGGCTTTAT CATGCAACATTAGTTTGCTTACCTTAAGAATTGCCCAAAAATGAAAGAAAATATGAGCTT TTCAGTTAAACATACTCCTAAAAACATTTTCCGGGATTTTACTACTAAAATTGGACATTT AAGCGAAGTAAAAGAGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAACACTTTAGGAG TCCAAGGCGGGCGGATCACTTGAGGTCAGGAGTTCAAGACCAGCTTGGCCAAGGTGATAA AACCCGTCTCTACTAATACAAAAAAAATTAGCTGGGTATGTTGGTGCAGGCTTGCAATCC CAGCTACTTGGGACGCTGAGGTGGGAGGATCGCCTGAACCTCAGAGGCAGAGGTTGCAAT GAAGCGGAGGTTGCAGTGAGCCGAGAGCATGCCGCTGCACTCCAGCCTGGGAGACTGCAT CTCAAAAAAGAAAAATAAACGAAGTAAAAGATATTTATCAGAGCTGTTACAGGAAGGTGT ATTTTTTAGCTATTTTGGCAGGGTGCTGTGGTGCTTGCATGTAGTCCCAGCTATTCAGGA ATATTGCTTGAGTCCAGCTTGGGCAACATAGCGAGACCCTATCTAAAATAACAATAATAT ATGGCCAGGCGGGATGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCA GATCACTTGAGGCCAGGAGTTCAAGACCAGCCCAACCAACATGGTGAAACCCTGTCTCCA CTGAAAATACATAAAATTAGCCGGGTGCAGTGGTGAGGCCTGTAATCCCAGCTACTCAGG AGGCTGAGGCAGGAGAATCGCTTGCACCCAGGAGGTGGAGGCTGCAGTAAGTCGAGATTG TGTCACTGCACTCTAGCCTGGGCGACAGAAAAAGAAAATTTAGGTGGGGAAAAAAATCAG AATTGCGTCTGTGGGAACAGGAATAAAGGAGAAACCACTATTGACTGGGAAGACACACAA AGAACTTTGTCAAAGTTGTATGGCTGAGGCCCACACGGTGGCTCACTTCTGTAATCCCAT CACTTTGGGAGGCTTAGGCAGAAGGATCACCTGAGATCAGGAGTTCCAGACCAGCCTGGC CAACATGGCGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCTTA CGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACAAGGTCAGGAGTTCG AGACCAGCCTGGCCAATATGGTGAAACCCCATCTCTACTAAAAATATAAAAATCAGCAAA AAAAATTTAGCCAGGCTTGGTCATGCATGCCTGTAATCCTAGCTACTGGGAAGGCTGAGG AAGGAGAATTGCTTGAACCCAGGTGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCACTGC TCTCCAGCCTGCATGACGGGAGTGAGACACCATCTCAAAAAATACATATAATAATATAAA TAAAAATATCTTTTTTGAAAATAATTTAATATACCATGTAATTTACCAGTTGAAGATGTT CGCTTTCAGAATATAATAAAAATAGTCAAAAA OMIM ID 611997