Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DDX54 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID79039
Official gene symbolDDX54
Full nameDEAD (Asp-Glu-Ala-Asp) box polypeptide 54
Aliases,DP97,MGC2835,
Gene summaryThis gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.13
Gene position113623284 - 113594978  Map Viewer
Gene orientationminus
Gene size28307 bp
Gene sequence
OMIM ID611665