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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KREMEN2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 79412 Official gene symbol KREMEN2 Full name kringle containing transmembrane protein 2 Aliases ,KRM2,MGC10791,MGC16709, Gene summary This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq] Location Chromosome: 16   Locus: 16p13.3 Gene position 3014217 - 3018381  Map Viewer Gene orientation plus Gene size 4165 bp Gene sequence >KREMEN2:2954217..2958381:Length=4165 GTAGAGGCTGAGGCACCGCCCAGAGCTCGCTGAGACAGAGACTGAGAACGCCCCCGGCCA GATTCCCCCCGGAGAGACCCGGGTAGGGACAGGGACAGAGAGACGCCTCTAGGGGCAGAG GCCCTGGGAGGCAAAGACCCCCAGGAGAGATTTACCCACCCCAGACGGAAAGCGCGGCTC AGAGTCGGACGAGGGGAGACTGTCAGAGGACAACGCCCCCTAGGTCTCCTGGGAGACCCC GAAGCGACCCCGGGGGCAGCCCGGGCCGTGTCCGGGCGAGGGTGACCTATCCTTGGTTGA GAGCGATGGGGACACAAGCCCTGCAGGGCTTCCTCTTTCTCCTCTTCCTCCCGCTGCTGC AGCCGCGTGGGGCCTCGGCTGGGAGCCTGCACAGTCCAGGTAAGTCCCCGCACGGCTGTC GGGCCGTGTTCACCACCCCTTCCTCGGCCTCCGCCCCCAGGGCCAGGCCCCCAAGGCTAG GGAGGGGGACAGAGCAGGTGGCCGGAGCAGCTGAGCAGCCCGAGGGCTCCTGCAGGGGCG GGTGCGGGGTCGCTGGCTGGGGACCCAGGCGGGAGGTGGCGTAGGGGCGCGAGGATGCCC GGCGTGGGTCCGGACCTCCCCAGGCCCTGCCTTTGCCGTGCAGGCCTGTCCGAATGCTTC CAGGTGAATGGGGCTGACTACCGCGGCCACCAGAACCGCACTGGCCCGCGCGGGGCGGGC CGCCCGTGCCTCTTCTGGGACCAGACGCAGCAACACAGCTACAGCAGCGCCAGCGACCCC CACGGCCGCTGGGGGCTGGGCGCGCACAACTTCTGCCGGTGAGGGGCGGGGCCTGCGCTG GGGGCGAGGCTGGGCTCACCATTGCAGGGATGGCCCGAAGCGGGGCCTCCGTGCGGGCGG GGTGGAGGTCTGCCGTGGACTGGCAGCCCAGCCTCCTGGAGAACCTGGGGGCGGGGCCAG AATGAGGGGCGGGGCGGGGCGGGGCGGGGCGCGCGGAACCCTGGCGCAAAAGGGATCCTC CTCAGGTGAACAATTTCTGCAGAGCTCCAGTTCAGGGCCAGGAGAGAAACGGACCTGGGC ACTCAAAGGACCCGTATGGGCGGGGCCTGGTCAGAGCGGGGGCCGAATGGGCGGGGCCTT GTCAGAGTGGGGCTCTTGTCATACAACTTATTTTGGGGTTCAGAGCCACAGCTACGGTCT GAGGCAGGATGGACCCAGCGGGAGGAGAGCCGCAAAGCTCAGGAGCTCACTTCTGCTTTT AAGTGGGGTTGGAGGCCAGGCGCGGTGGCTCAGCCTGTAATCCCAGCACTTTGGGAGGCC AAGGCAGGCGGATCATCTGAGGTCAGGAGTTCGAGACCAGCCTGGCTACCATGGTGAAAC CCCATTTCTACTAAAAATACAAAAAATTAGCGGGGCATGGTGGCGGGCGCCTGTAATCCC AGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGCTTGCAGTG AGCAGAGATCGCGCCAATGCACTCTAGCCTGGGTGACAGAGCGAGACTCGTCTCAAAAAA AAAAAAAAAAAGTGGGGTTTGAGGGACGGAAGTGGCTGAGGCCCATGCCGGGTGGGGGTG AAGAATACAGATGGCCTCAAAGTCCTCATATATGGAGTCAAGTCTAGCAACAGCTGAAGC CTAAAAACAGCTCTCAAGTCCCCTTTAATGACTTCCCGCTGTCCACTCGGAAGTCGACGT CCAGTTCCTTCATCAGGCAGAGTTCTGCGTAGACAAAACTGGAATTTGTGGGTGTACAGC AGGCAGCACAGCCGCTCACAGGCACAGAGCCTTGAAGGCCACTTTGAGCATAGGCTGCGG GGCCGGGCCTGGGTTTGCTATTCTTGGGGTGGTGGGAGCCCCACCACCTCCCTCCCACCC GCAGTAACCCAGACGGTGACGTGCAGCCGTGGTGCTACGTGGCTGAGACAGAGGAGGGCA TCTACTGGCGCTACTGCGACATCCCCTCCTGTCACAGTGAGTAGCGCGGCTGGACAGAGG TGGGAACGCTGCTGCATCTGGGAGGAGGGTTGTTTTCGGAGTCACGGAAGTCTGACTCTG CCCCCTCAGTGCCAGGCTACCTGGGATGCTTTGTGGACTCAGGGGCACCCCCAGCCCTCA GCGGCCCCAGCGGCACCTCCACGAAGCTCACGGTCCAGGTGTGCCTACGCTTCTGCCGCA TGAAGGGGTACCAGGTACTGCTCACGGGCCCAGACCAGTGACCCCTGACCTGGACCTAAA GACCACACTCAACTCCCAACACTCGGTTGCCAAACCCAGACACCGGTTTCTGAACCTCCA GCCCGATTCCCACCCCGACCCCAGGCCCCCACCACTTCACCCCTACCCCAGCCCCTGCCC TGGGGTCACCCAGTCTGTGCTCCCAGCTGGCGGGCGTGGAGGCCGGTTACGCCTGCTTCT GTGGCTCTGAAAGCGACCTGGCCCGGGGACGCCTGGCCCCCGCCACCGACTGTGACCAGA TCTGTTTCGGCCACCCTGGACAGCTGTGTGGCGGCGATGGGCGGCTGGGCGTCTATGAAG GTGAGGAGTGGGCGGGGACCAGGGGCCTGGGCGGGCCTCGAGGTGGGGCCTGGCCGGGCA GGGGAGCCGCCGTGTCCTGGTCCTCAGGATGCTGACTGCCGGCCCCGCCCGCAGTGTCGG TGGGCTCCTGCCAGGGGAACTGGACAGCGCCTCAGGGCGTCATCTACTCCCCGGACTTCC CGGACGAGTACGGGCCGGACCGGAACTGCAGCTGGGCCCTGGGCCCGCCAGGCGCCGCGC TGGAGCTCACCTTCCGCCTCTTCGAGCTGGCCGACCCGCGCGACCGGCTGGAGCTGCGCG ACGCGGCTTCGGGCAGCCTGCTCCGCGCCTTCGATGGCGCCCGCCCACCGCCGTCCGGGC CGCTGCGCCTGGGCACTGCCGCGCTGCTGCTCACCTTCCGAAGCGACGCGCGCGGCCACG CGCAAGGCTTCGCGCTCACCTACCGCGGTGAGCCTCAGCTCGGCGCGCCCTGCCCGCTGT TCCCACCCCGCTCTCCCCACCCCGCCTCACGCCCCTCTCCGCAGGGCTGCAGGACGCCGC TGAGGACCCAGAGGCCCCCGAGGGCTCGGCCCAGACCCCCGCGGCGCCCCTCGACGGGGC CAACGTGAGCTGCAGCCCCAGGCCTGGGGCTCCGCCGGCCGCGATTGGGGGTGAGGCGGG CGCGCGGGACGGGAGTGAGTCAGGGAGCCGCCCCCTCGCGCCCATCCTCACCGCAGCCGT GTGCCCGCAGCCCGGGTCTTCTCGACGGTGACGGCTGTCTCGGTGCTGCTGCTGCTGCTC CTGGGGCTGCTGCGTCCGCTGCGCCGACGGTGCGGGGCGCTGGGGCAGGGCCTGAGGGCG GACCGGTGGTGGGGAGCTGGAGCCCCAGAAGGGAACAGAGCTAGGAAGGAACTCCTGGGT TCTTAAGGGAGCGAGGCTTTGGGTCCACGCACAGGATCGCGCGCGGGATCGCAGGTAGAG CAGGACGCTGCAGCGGGATTGGACCGGCTCGGCTGATGTCTGCTCCCTCTCTAGGAGCTG TCTGCTGGCTCCGGGAAAAGGGCCCCCGGCGCTGGGGGCTTCCAGGGGCCCCAGGAGAAG CTGGGCTGTGTGGTACCAACAGCCCCGAGGGGTGGCCTTGCCCTGCTCCCCCGGGGACCC CCAGGCTGAGGGTTCTGCCGCGGGCTACCGGCCTCTGAGTGCCTCCAGCCAGAGCTCCCT GCGCTCGCTCATCTCCGCTCTCTGACTCTGGGCCCCGAGGGTCCGCTGGGCCCGCCGCCG GCGAGATGGACACCTGAGATGCTGTGCTGCGCCCTGCCTCGGCCTTGCGCCTGTGTAGGG GCAGCTCGGCCTCTGGTCGCCTTGGGGAGACCAAAAGTCGGACAGGAAACATCTGGTGCT ATTATCTGGGACTTGGCCTGACCGTGGGGGTCCAGATGGTCCAGGCCCTCTCCATGGACC TGTATGTGGGGGTGGTCTCTGGTTTCGGAGGTCTTTGAACCCCTCTGGGGGTGGTCCTGG ACTGCCGTCCTCAGTGAGAGGTCACAGGTCAGCAAAAACAGTCAAAAAACCCCCACAGAT TTTGAATAAAGGATCTACTTTGGTA OMIM ID 609899