Entrez gene ID | | 79576 |
Official gene symbol | | NKAP |
Full name | | NFKB activating protein |
Aliases | | ,FLJ22626, |
Gene summary | | This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq24 |
Gene position | | 119077735 - 119059013 Map Viewer |
Gene orientation | | minus |
Gene size | | 18723 bp |
Gene sequence |
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OMIM ID | | 300766 |
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