Entrez gene ID | | 79840 |
Official gene symbol | | NHEJ1 |
Full name | | nonhomologous end-joining factor 1 |
Aliases | | ,FLJ12610,XLF, |
Gene summary | | Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q35 |
Gene position | | 220025587 - 219940046 Map Viewer |
Gene orientation | | minus |
Gene size | | 85542 bp |
Gene sequence |
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OMIM ID | | 611290 |
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