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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HMGA2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID8091
Official gene symbolHMGA2
Full namehigh mobility group AT-hook 2
Aliases,BABL,HMGI-C,HMGIC,LIPO,STQTL9,
Gene summaryThis gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q15
Gene position66218240 - 66360071  Map Viewer
Gene orientationplus
Gene size141832 bp
Gene sequence
OMIM ID600698