| Entrez gene ID | | 8099 |
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| Official gene symbol | | CDK2AP1 |
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| Full name | | cyclin-dependent kinase 2 associated protein 1 |
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| Aliases | | ,DOC1,DORC1,ST19,doc-1,p12DOC-1, |
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| Gene summary | | The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes. [provided by RefSeq] |
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| Location | | Chromosome: 12 Locus: 12q24.31 |
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| Gene position | | 123756687 - 123745538 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 11150 bp |
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| Gene sequence |
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| OMIM ID | | 602198 |
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