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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CAMK2A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID815
Official gene symbolCAMK2A
Full namecalcium/calmodulin-dependent protein kinase II alpha
Aliases,CAMKA,KIAA0968,
Gene summaryThe product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q32
Gene position149669403 - 149599054  Map Viewer
Gene orientationminus
Gene size70350 bp
Gene sequence
OMIM ID114078