| Entrez gene ID | | 81704 |
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| Official gene symbol | | DOCK8 |
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| Full name | | dedicator of cytokinesis 8 |
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| Aliases | | ,FLJ00026,FLJ00152,FLJ00346,MRD2,ZIR8, |
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| Gene summary | | This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. |
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| Location | | Chromosome: 9 Locus: 9p24.3 |
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| Gene position | | 214865 - 465259 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 250395 bp |
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| Gene sequence |
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| OMIM ID | | 611432 |
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