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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADAMTS12 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID81792
Official gene symbolADAMTS12
Full nameADAM metallopeptidase with thrombospondin type 1 motif, 12
Aliases,PRO4389,
Gene summaryThis gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q35
Gene position33892124 - 33527286  Map Viewer
Gene orientationminus
Gene size364839 bp
Gene sequence
OMIM ID606184