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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TLR10 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 81793 Official gene symbol TLR10 Full name toll-like receptor 10 Aliases ,CD290,MGC104967,MGC126398,MGC126399, Gene summary The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 4   Locus: 4p14 Gene position 38784589 - 38774234  Map Viewer Gene orientation minus Gene size 10356 bp Gene sequence >TLR10:complement(5933596..5943951):Length=10356 GAATCATCCACGCACCTGCAGCTCTGCTGAGAGAGTGCAAGCCGTGGGGTAAGAACCTTA GCTTTGTTTGTTGTAACTCTCATTAAAAAGATATAAGGGCTGCATGGGTATTTTCTAAAA AGGAGATAATTTGAGCTAATATTGAGGGGAGGGAAGTAGGGTTATTTAGATTTTTAGTAT TTACTATTTTGTCTAGATTAATGATTAGTGACCTTGGGGCTATTGATCTGAGGAATTTCT TGCAGATGCTTGAGAGCGTGGGTTTCTTTTCACTGATTGCGGATCAAACCTGGTCAGCTC TTCTATTCAGATTGAACGGTCCTATGCACTGTGGCAAGTTTTTTCTAGCTCTTATTTCCC CACAGCGTATGTTAACCTCTGCTGGATGAAACCTTTGGCTATTTAAGGCATATTTGTTGC TCCTTTACCCCGTTGAAAAGTTCTGCATTTGTGTTACCTGTTTAAAAGTAGGGGCAGATC TGATGGATCTTGTACAATGCAGTTCTTATTCCGTTTCCTTCAGAAGTGGACAAAGAGGGC CATATGTGGTTGCTGTAAAGAAGAGGATGGTTAACAACCTGTGAGCATTTGGTTTCTTGA TAAGCTTTCTCCCAGACCACCTACACTGAGCTATTAATTAGGAATAGGATGCACTTCGAG TTTTATTTCAATTCTTGTGAACTTATAACTTTCCTAAGAATATATTTATACATGTAGGCA AAGTCTCTTGAACTTTGTGGCACCTAGCAGAGTGTCCCACAGCAGCTGCATGAAGCTTCA TAGACAGGGGCATGGGGTGAGAAAGGAGGAAGTGGCCGCCATGGCAGCTGGTCAGATCAA TGGATTCAACCTCAGTGATTCGGTCCTTAGGATGTCGTTACATCTTAAGCCACCTCATTT CAAGGTTTGAGGTGCCTTGCATTTGGGTTTAGTTACCATCCAGAAGGAACCAGACAGGTC TGGGTTCAAATCTCTGCTTCTTCAGTTGGTCATCTTGGGCAAGTTACTTTACCTCTGGGC TTTAGCTCCTCCATCTGTAAAATATGAATAATAATGGCCGCCATTTTGTTGAGTCATTGA GGGATTAAACAAGGTAATGGACATAAAACACTTAGCTCCATGTCAGACACGTAGGAAATA CTGAAAAGAAGTCATTCTTACTCTTATGTTGCAAAGATCATTCAACATTCAATAGGTTCT TAATCTCTTTTCTATTTCTTTATATCATTGGGAAAAGATAAATTAGATGATTAAATATTC TTTGGTAAAACACTAGTTGTCATTTGATGATGTCTTTTGACTTGGACTTTTAAATTATAA GATATTAAAGATGTATTAAGGAAGGTCATTCTCTGTTTTTTACCTGCTTTTAACGTAGTA GTAGGGATATGATATTAACATATATATACTATTTATAGACTACATCACCAACATGGTGAA ACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGTGTGATGGCAGGTGCCTGTAATCC CAGCTACTCAGGAGGCTGCGGCAGGAGAATCGCTTGAACCTGGGAGGTGGAGCTTGCAGT GAGCTGAGATCATACCACTTTACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCAAAA AAAAAAAAAAGTGTATGTCCTACTTTTAAAATTGCTTTAATGAGGCCAAGCACAGTGGCT CACACCTCTAATCACACCCATTTGGGAGGCTGAGGTGGGAAGATTGCTGGAGGCCAGGAG TTTAAGAGCAGCCTTGGCAACATAGTGAGACCCTGTCTCTATGTAAAAGTTGTTTTTATA AAATGTCATAATGCATAAGTATTGCCTGAGAGATAGGACCTTTACTATTGTTATATTAAG AGAAGTTCAAAAAGAGTTCCTCTCCCATTGTAGTCCCAGATAAGACTGTGGTATTGGGCA GGGGGAAGAAGTGGGTAAGAGATAGAAACTCTGACTTCTCAGCGCAGAGTTCCAGCTAAA GCAACTGGGTTAGATTCTGCTGCATTCTTAAGGGGCCATGGCTCTAAGACCTAGAAGCTT AAAGTCAATTGCTACAAATTAAGCACTCTATGAGAGGATAACATTAAAAGCACCTTTGTC AACCTAATGATTATAACTGCCAGGGTCCTATCAAGCCATAATAGAGCCTGAGGCAAAAGA AACAATCAGCAATACTGATCCTGTCTTTATGAAAAATTTCGATATTTTGTTCAACATAGA TTTTTGCATTAATTTTCATTTTTAAAAATATTTCATGTAAACATTATCTTGATTACTGAG TTCCTTGGGACCCCCTTAACATTTATGCCTTCCTTGCTTCACCCGAGTCTTGACCTGATA ACTGCCACCATTTATTAAGTGTGATATGCTAGGCATGGTACTAAGTGACTTACATACATT GTCTTATGCCTCTTCACAAGCTCCATTTTACAGATGACAAAACCAGATCTTTCAGAGATT AAATAAATGGTCCGAGTACATAGCTAATGAGTGGATGAATGGTTAACATTGGATTTGAAC ACAGATCCATCAATCACTAAAACCAAACTTATTCTTTTTTTTTTTGAAACTGAGTCTTGC TCTGTTGCCCAGGCTGGAGTGCAGTGGTGGCATCTCAGCTCACTGCAACCTCCACCTTTT GGGTTCAAGTGATTATCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACATGCCA CCACGCTCAGCTAATTTTTTGTATTTTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCA GGATGGTCTTGATCTCCTTACTTTGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGA TTACAGGCCTGAGCCACCGCGCCAGGCCTACCAAACTCATTCTTCAACCATCATGCCCTG CACTGTATCAGGAATTCACAACATAAATTCATTCATTCAACACATATTTATGAGAGCATA TTATGCATCACGTTGTACTAAGGATTAAAACGTTGAAATTCATACATACAAGGATTCATT CATTCATATGTGCATTCAACAAGCAGTAATGAGCAGGCACCATGTGTCAAGCACTATGCT ACATGCTGAGGATACAGAAGTGAACAAGACAGACAGCTACCACGGGAATGAACAGAGAAG GGACAGGTGACAAGCAAATGAATGAAAGTTTATTTACTAAGAGGTCATTCAGAAGAGATC ATGAATTCATGGAAAATTATTTTCTGCATCTAGTGGCATGGAAATTAAGATATTCTGAAT TTTAATGTATAGTTTTAAGAAAACTGAAAGAAAATATAAAGTTTATCATTATACATTGGA TACTATGAACACAATAATTTGAGTAGTAATTACACTTCCAGGCCACAGTTGTAAACTGAT TTTCTATTAGAAATATTTAAAAGTAGATGTAGAAAACTTACTCTTAAATATATAACAGTT CAAAAATCCAGCAGGAACTAAGTTAATTAAATAGAATATTCACCTGTTTTTTCTGATAAT TATCCTGTGTTATATTTACATATTAATGCAGTATAATATTTTAGTATACATTACACTCTA GGGAGTCACTGAAATGTCAGCAAAGAAAAATACGGCCGGAGGCATCTTAAGTCATTTGAC CACGTTTTTAAAAGTTGGTGTTTTGAGAAATCATCTAAATGTGGTGACCTTACCAAAATG ATTGCTTTTTCTCCAAGATATTTGAGAACACTTACCAGAAACAATAGTTTATGAAATATA AAAATTATATGATCAATGTGGATAATTAATATTTTTACAAAGGAATTCTCCAAGTTTACA TTGTAAGGGAGTTCACACAAAGAAACTATGATCATATGTGTTCCCAAGATAAGAGATAAG ATGCTCTCTCTCCTTTACTAGTATCAGCAGCTAATGGAAAACTTGGGAGTGGCCCTCTCA CTCCCTACTCTCCATAGGTTTTCTGGAATTTCTTCACTTCAAGAAAAAAACCAGACTTGG GAAGGTTCTAGAGAAAGAGAAATACAGATGAGAGAGAGGTAACATTCTAAGTGGCCTTAT GTTTTGATTCTGCCCCACCTTTGTTACCCTGCCATGTTTGTGTGCATTCCTGTGGATGGG CGTGCCCACTGCCTCCCTCACCTCCCATCCAGGCTTTCAGAATGATGGGAACATGACACG CACAGAGAATTCTCTCTAACCCATCCTCTTTCTGTTGAGCATATCTTTTGCTCCCTCTGC TTGTCTATGGGAGTGACCTGTCTGAGGGAGGTTGAGGGTCAATGTGTAACAGATACATAC AAATGGAAGCAGAAAAACTCCCCCACTAACTTATCACCTGCTCTTGGTGCCTTCAGAGAG CCTGGTGTGGGGACACGTAGAGTTAAATTGTTTACTAATTTGAAATTAGAATCTAACCAC TTCTCTCCACTTCCATTGATACATTCTCTCTGGCACAAGTTACGCTATAGTGTCCCAAGG AGTCTTCCCTGCCAGCCTTGTGGCTCCCAGTCATTTCCACCCAACAAACAGAGGAATCTT TTTATTTGTTTGTTTGTTTATTTATTTATTTATTTATTTTATACTGTAAGTTCTGGGGTA CATGTGCGGAACGTGCATGTTTGTTACATAGGTATACACATGCCATGGTGGTTTGCTGCA CCCATCAGCCCATCATCTACATTAGGTATTTCTCCTAATGCTATTCCTCCCCTAGCCCCC CACCCCCTGACAGGCCCCGGTGTGTGTCAATGTGTTCTCATTGTTCAACTCCCAGTTATG AGTGAGAACATGTGGTGTTTGGTTTTCTGTTCTTGTATTAGTTTGCTGAGAATGATGGTT TCCAGATTCATCCATGTCCCTGCAAAGGACATGAACACATTCTTTTTTATGGCTGCATAG TATTCCATGGTGTATATGTGCCATATTTTCTTTATCCAGTCTATCATTGATGGGCATTTG GGTTGGTTCCAAGTCTTTGCTGTTGTGAATAGTGCTGCAATAAACACGTGTGTGCATGTA TCTTTATAGTAGAATGATTTATAATCCTTTGGATAGATACCCAGTAATGGCATTGCAGGA TCAAATAGTATTTCTAGTTCTAGATCCTTGAGGAATCGCCACATTGTCTTCCACAATTGT TGAGCTAATTTACACCCCCACCAACAGTGTAAAAGCGTTCCTATTTCTCTACACCCTCTC CAGCACCTGTTGTCTCCTGACTTTTTAATGATCACCATTCTAACAGGCATGAGATGGTAT CTCATTGTGGTTTTGATTTGCATTTCTCTAATGACCAGTGATCATGAGCTTTTTTTCATA TGTTTGTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGCCTGTTCATATCCTTCACCCAC TTTTTGATGGGGTTGTTTTTTTCTTGTAAATTTTTTAATGTTCTTTATAGATTCTGGGTA TTAGCCCTTTGTCAGATGGACAGATTGCAAAAATTTTCTCCCATTCTATAGGTTGCCTCA AACAGAGGAATCTTTAAAATGTATGTCAGAACCTGTCATTCCTGGACTCTAAATCTTCTG CTGGTTTCTTATTTCAGTCAGAGGAAAATTGCCAAGTTCTTATAAGATCCGACCTCTTCT CTGATTCCGTCCCCTAACTCCACTCCAGGTCTTCCTCACATTTTCCAAGCACATCAGGAT CTTTAAATTTGTACTTGCTGTTCTCTCTCTCTCCAAAATACTCTTTCCCCAGACAACAAG TGTCTTGCTTCTTTGGCCCCTTTAGATTTCTGCATGAAGATCACTATCAGGGAGGCCATT TTTGATCATTCTATAAAAAAGAAAATCACTCCCCAGTCTCTCTCTGTTTCCCTTATCTTA GTTATTTTTCCTTCAAGACAATATCACTGCCTGATATTGGTCCCCACCCAAATCTCATCT TGAACTGTAGCTCCCATAATTCCCACATGTTGTGGGAGGGACCTGGTGGGAAGTAATTGA ATCATGGGGGCGGGTCTTTCCCATGCTGTTCTCATGATAGTGAATAAGTCTCATGAGATC TGGTGGTTTTATAAAGAGGAGGTTCCCTGCACATGCTCTCTTGCCTGCTGCCACATAAGA CATGACTTTGCTCCTCATTCGCCTTCCACCATGATTGTGAGGCCTCCCCAGGCATGTGGA ATTGTGAGTCATAACATATAAACGTATTGTTTTGTTTGCAGTCTCTCTTTTCTTAACTTC TTTCTAGAATATAAGCTATGTAGAAACAGAAATCTCTTCTGTTCACTGCTACTTCCCCAG TGCCTAGAAAAGTTTCTGGCAGAATAGGTACTTAATAAATATCTTGAATAATGAATATCG TAAAATCTTAGTACTCCAACTACCTCTGTTCTACGTCTAATCCAACCACGTGAAGCCTGG CACATCTCCCAAAGTCCTCAGAATTCTATATCCTTCAATTTCCTCATCTATCAAATGGGA GTAGTAGTACTTCCCTCACAGAGTATGGTGATAAATAAATGAGATAATATACATGAAGCA ATTAGTATGTATCTTGGCACATTGAAATCTAACCTGAAAGCTTTGATTCTATGCCATAAC AGAATTCAGCAGCTGAATATCAAGACCTTTGAATTCAACAAGAAGTTAAGACATTTATAG TTGTCTAACAACAGACTGAAGATTGTGGCTTGGTATTCACTGGCAGGTTTCAGACATTTA GATCTTTCTTTTAATGACTAACACCATGCCTATCTGTGGAGAAGCTGGCAACATGTCACA CCTGGAAATTGTTTTTCAACATTAATACTATTATTTGGCAGTAATCCAGATTGCTTTTGC CACCAACCTGAAGACATATAGAGGCAGAAGGACAGGAATAATTCTATTTGTTTCCTGTTT TGAAACTTCCATCTGTAAGGTAAGTGTTGAAAGTCAGATATTGGCTCCAGGGACTTTCTA TATCCACAAATACAAAAATTGAGGGGTAACTCCTTGATATCAAGTCAAAGGCTCACAATG TCTGGTAATAAAACAAATTACTTTCAATTTTCTTGAAATCTTCAGGCTATCAAAAGGAGA TGTGAGAGAGGGTATTGAGTCTGGCCTGACAATGCAGTTCTTAAACCAAAGGTCCATTAT GCTTCTCCTCTCTGAGAATCCTGACTTACCTCAACAACGGAGACATGGCACAGTAGCCAG CTTGGAGACTTCTCAGCCAATGCTCTGAGATCAAGTCGAAGACCCAATATACAGGTTGGA ACCTTACTCCAACCTCTTGATGAATGTAGTCAGATGTTGGCATTTTTTTTGCAAATAAAA ATCCTACAGGATTTAACAAACCAAATAAAAATCTAATATTATATACTTTTTTTTAGGGTT TTGAGCTCATCTTCATCATTCATATGAGGAAATAAGTGGTAAAATCCTTGGAAATACAAT GAGACTCATCAGAAACATTTACATATTTTGTAGTATTGTTATGACAGCAGAGGGTGATGC TCCAGAGCTGCCAGAAGAAAGGGAACTGATGACCAACTGCTCCAACATGTCTCTAAGAAA GGTTCCCGCAGACTTGACCCCAGCCACAACGACACTGGATTTATCCTATAACCTCCTTTT TCAACTCCAGAGTTCAGATTTTCATTCTGTCTCCAAACTGAGAGTTTTGATTCTATGCCA TAACAGAATTCAACAGCTGGATCTCAAAACCTTTGAATTCAACAAGGAGTTAAGATATTT AGATTTGTCTAATAACAGACTGAAGAGTGTAACTTGGTATTTACTGGCAGGTCTCAGGTA TTTAGATCTTTCTTTTAATGACTTTGACACCATGCCTATCTGTGAGGAAGCTGGCAACAT GTCACACCTGGAAATCCTAGGTTTGAGTGGGGCAAAAATACAAAAATCAGATTTCCAGAA AATTGCTCATCTGCATCTAAATACTGTCTTCTTAGGATTCAGAACTCTTCCTCATTATGA AGAAGGTAGCCTGCCCATCTTAAACACAACAAAACTGCACATTGTTTTACCAATGGACAC AAATTTCTGGGTTCTTTTGCGTGATGGAATCAAGACTTCAAAAATATTAGAAATGACAAA TATAGATGGCAAAAGCCAATTTGTAAGTTATGAAATGCAACGAAATCTTAGTTTAGAAAA TGCTAAGACATCGGTTCTATTGCTTAATAAAGTTGATTTACTCTGGGACGACCTTTTCCT TATCTTACAATTTGTTTGGCATACATCAGTGGAACACTTTCAGATCCGAAATGTGACTTT TGGTGGTAAGGCTTATCTTGACCACAATTCATTTGACTACTCAAATACTGTAATGAGAAC TATAAAATTGGAGCATGTACATTTCAGAGTGTTTTACATTCAACAGGATAAAATCTATTT GCTTTTGACCAAAATGGACATAGAAAACCTGACAATATCAAATGCACAAATGCCACACAT GCTTTTCCCGAATTATCCTACGAAATTCCAATATTTAAATTTTGCCAATAATATCTTAAC AGACGAGTTGTTTAAAAGAACTATCCAACTGCCTCACTTGAAAACTCTCATTTTGAATGG CAATAAACTGGAGACACTTTCTTTAGTAAGTTGCTTTGCTAACAACACACCCTTGGAACA CTTGGATCTGAGTCAAAATCTATTACAACATAAAAATGATGAAAATTGCTCATGGCCAGA AACTGTGGTCAATATGAATCTGTCATACAATAAATTGTCTGATTCTGTCTTCAGGTGCTT GCCCAAAAGTATTCAAATACTTGACCTAAATAATAACCAAATCCAAACTGTACCTAAAGA GACTATTCATCTGATGGCCTTACGAGAACTAAATATTGCATTTAATTTTCTAACTGATCT CCCTGGATGCAGTCATTTCAGTAGACTTTCAGTTCTGAACATTGAAATGAACTTCATTCT CAGCCCATCTCTGGATTTTGTTCAGAGCTGCCAGGAAGTTAAAACTCTAAATGCGGGAAG AAATCCATTCCGGTGTACCTGTGAATTAAAAAATTTCATTCAGCTTGAAACATATTCAGA GGTCATGATGGTTGGATGGTCAGATTCATACACCTGTGAATACCCTTTAAACCTAAGGGG AACTAGGTTAAAAGACGTTCATCTCCACGAATTATCTTGCAACACAGCTCTGTTGATTGT CACCATTGTGGTTATTATGCTAGTTCTGGGGTTGGCTGTGGCCTTCTGCTGTCTCCACTT TGATCTGCCCTGGTATCTCAGGATGCTAGGTCAATGCACACAAACATGGCACAGGGTTAG GAAAACAACCCAAGAACAACTCAAGAGAAATGTCCGATTCCACGCATTTATTTCATACAG TGAACATGATTCTCTGTGGGTGAAGAATGAATTGATCCCCAATCTAGAGAAGGAAGATGG TTCTATCTTGATTTGCCTTTATGAAAGCTACTTTGACCCTGGCAAAAGCATTAGTGAAAA TATTGTAAGCTTCATTGAGAAAAGCTATAAGTCCATCTTTGTTTTGTCTCCCAACTTTGT CCAGAATGAGTGGTGCCATTATGAATTCTACTTTGCCCACCACAATCTCTTCCATGAAAA TTCTGATCATATAATTCTTATCTTACTGGAACCCATTCCATTCTATTGCATTCCCACCAG GTATCATAAACTGAAAGCTCTCCTGGAAAAAAAAGCATACTTGGAATGGCCCAAGGATAG GCGTAAATGTGGGCTTTTCTGGGCAAACCTTCGAGCTGCTATTAATGTTAATGTATTAGC CACCAGAGAAATGTATGAACTGCAGACATTCACAGAGTTAAATGAAGAGTCTCGAGGTTC TACAATCTCTCTGATGAGAACAGATTGTCTATAAAATCCCACAGTCCTTGGGAAGTTGGG GACCACATACACTGTTGGGATGTACATTGATACAACCTTTATGATGGCAATTTGACAATA TTTATTAAAATAAAAAATGGTTATTCCCTTCATATCAGTTTCTAGAAGGATTTCTAAGAA TGTATCCTATAGAAACACCTTCACAAGTTTATAAGGGCTTATGGAAAAAGGTGTTCATCC CAGGATTGTTTATAATCATGAAAAATGTGGCCAGGTGCAGTGGCTCACTCTTGTAATCCC AGCACTATGGGAGGCCAAGGTGGGTGACCCACGAGGTCAAGAGATGGAGACCATCCTGGC CAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGATGGTGCA CGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGT GGCAGTTGCAGTGAGCTGAGATCGAGCCACTGCACTCCAGCCTGGTGACAGAGCGAGACT CCATCTCAAAAAAAAGAAAAAAAAAAAAGAAAAAAA OMIM ID 606270