Entrez gene ID | | 81794 |
Official gene symbol | | ADAMTS10 |
Full name | | ADAM metallopeptidase with thrombospondin type 1 motif, 10 |
Aliases | | ,ADAM-TS10,WMS, |
Gene summary | | This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.2 |
Gene position | | 8675588 - 8645126 Map Viewer |
Gene orientation | | minus |
Gene size | | 30463 bp |
Gene sequence |
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OMIM ID | | 608990 |
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