Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADAMTS10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID81794
Official gene symbolADAMTS10
Full nameADAM metallopeptidase with thrombospondin type 1 motif, 10
Aliases,ADAM-TS10,WMS,
Gene summaryThis gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.2
Gene position8675588 - 8645126  Map Viewer
Gene orientationminus
Gene size30463 bp
Gene sequence
OMIM ID608990