Entrez gene ID | | 8290 |
Official gene symbol | | HIST3H3 |
Full name | | histone cluster 3, H3 |
Aliases | | ,H3.4,H3/g,H3FT,H3t,MGC126886,MGC126888, |
Gene summary | | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q42 |
Gene position | | 228613026 - 228612546 Map Viewer |
Gene orientation | | minus |
Gene size | | 481 bp |
Gene sequence |
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OMIM ID | | 602820 |
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