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Gene information for CARS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID833
Official gene symbolCARS
Full namecysteinyl-tRNA synthetase
Aliases,CARS1,CYSRS,MGC:11246,
Gene summaryThis gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p15.5
Gene position3078681 - 3022152  Map Viewer
Gene orientationminus
Gene size56530 bp
Gene sequence
OMIM ID123859