Entrez gene ID | | 8335 |
Official gene symbol | | HIST1H2AB |
Full name | | histone cluster 1, H2ab |
Aliases | | ,H2A/m,H2AFM,HIST1H2AE, |
Gene summary | | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p21.3 |
Gene position | | 26033796 - 26033320 Map Viewer |
Gene orientation | | minus |
Gene size | | 477 bp |
Gene sequence |
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OMIM ID | | 602795 |
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