Entrez gene ID | | 83463 |
Official gene symbol | | MXD3 |
Full name | | MAX dimerization protein 3 |
Aliases | | ,BHLHC13,FLJ35523,MAD3,MGC2383,MYX, |
Gene summary | | This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q35.3 |
Gene position | | 176739292 - 176732501 Map Viewer |
Gene orientation | | minus |
Gene size | | 6792 bp |
Gene sequence |
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OMIM ID | | 609450 |