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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for JAM3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID83700
Official gene symbolJAM3
Full namejunctional adhesion molecule 3
Aliases,FLJ14529,JAM-C,JAMC,
Gene summaryTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q25
Gene position133938820 - 134021649  Map Viewer
Gene orientationplus
Gene size82830 bp
Gene sequence
OMIM ID606871