Entrez gene ID | | 8398 |
Official gene symbol | | PLA2G6 |
Full name | | phospholipase A2, group VI (cytosolic, calcium-independent) |
Aliases | | ,CaI-PLA2,GVI,INAD1,IPLA2-VIA,NBIA2A,NBIA2B,PARK14,PLA2,PNPLA9,iPLA2, |
Gene summary | | The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q13.1 |
Gene position | | 38577761 - 38507502 Map Viewer |
Gene orientation | | minus |
Gene size | | 70260 bp |
Gene sequence |
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OMIM ID | | 603604 |
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